PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8889285-2 1996 Apomorphine did not change BP and HR but significantly decreased PRL plasma levels in controls as well as in the two groups of PD patients. Apomorphine 0-11 prolactin Homo sapiens 65-68 12943941-0 2003 Growth hormone and prolactin response to apomorphine in bipolar and unipolar depression. Apomorphine 41-52 prolactin Homo sapiens 19-28 12943941-2 2003 This was investigated by measuring growth hormone (GH) or prolactin (PRL) response to apomorphine (APO), a dopamine receptor agonist, in patients with bipolar depression, unipolar depression and control subjects. Apomorphine 86-97 prolactin Homo sapiens 58-67 8889285-6 1996 These results show that hypothalamic dopaminergic sensitivity (studied through GH and PRL responses to apomorphine) is normal in PD. Apomorphine 103-114 prolactin Homo sapiens 86-89 1594706-5 1992 Twelve patients received an apomorphine challenge; a trend toward a significant inverse relationship was found between baseline dyskinesia and apomorphine-induced decreases in plasma PRL. Apomorphine 28-39 prolactin Homo sapiens 183-186 7870845-6 1994 Significant correlations were observed between negative symptoms and GH responses to clonidine (negative), between negative symptoms and PRL responses to apomorphine (positive), and between positive symptoms and PRL responses to apomorphine (negative). Apomorphine 154-165 prolactin Homo sapiens 137-140 7870845-6 1994 Significant correlations were observed between negative symptoms and GH responses to clonidine (negative), between negative symptoms and PRL responses to apomorphine (positive), and between positive symptoms and PRL responses to apomorphine (negative). Apomorphine 229-240 prolactin Homo sapiens 212-215 1594706-5 1992 Twelve patients received an apomorphine challenge; a trend toward a significant inverse relationship was found between baseline dyskinesia and apomorphine-induced decreases in plasma PRL. Apomorphine 143-154 prolactin Homo sapiens 183-186 3977547-7 1985 Percent PRL level decrease after apomorphine administration was significantly greater in normal subjects than in schizophrenics. Apomorphine 33-44 prolactin Homo sapiens 8-11 2243892-3 1990 In addition, the functional responsivity of DA receptors was assessed in the same group of patients by measuring the change in plasma PRL and GH concentrations following the administration of the direct-acting DA agonist, apomorphine (0.01 mg/kg, s.c.) or saline. Apomorphine 222-233 prolactin Homo sapiens 134-137 6721674-0 1984 Growth hormone and prolactin response to apomorphine in schizophrenia and the major affective disorders. Apomorphine 41-52 prolactin Homo sapiens 19-28 2866563-6 1985 apomorphine increased growth hormone in serum from 1.8 +/- 0.2 to 28.3 +/- 4.6 ng/ml and reduced prolactin by 57 +/- 7%. Apomorphine 0-11 prolactin Homo sapiens 97-106 6497565-2 1984 Growth hormone and prolactin (PRL) responses to 0.75 mg of apomorphine hydrochloride were measured in 19 newly admitted psychotic patients who had been untreated by neuroleptic or antidepressant drugs for at least nine months. Apomorphine 59-84 prolactin Homo sapiens 30-33 6721674-2 1984 The responses of serum prolactin (PRL) and growth hormone (GH) to the dopamine agonist apomorphine hydrochloride (0.75 mg subcutaneously) were studied in a large group of unmedicated hospitalized patients with functional psychoses. Apomorphine 87-112 prolactin Homo sapiens 23-32 6721674-8 1984 The apomorphine-induced PRL suppression correlated significantly with various measures of depression across diagnostic groups. Apomorphine 4-15 prolactin Homo sapiens 24-27 6411776-0 1983 Effect of subchronic lithium treatment on apomorphine-induced change in prolactin and growth hormone secretion. Apomorphine 42-53 prolactin Homo sapiens 72-81 540209-1 1979 Apomorphine, a direct-acting dopamine agonist, stimulates release of growth hormone (hGH) and suppresses release of prolactin (PRL) from the anterior pituitary. Apomorphine 0-11 prolactin Homo sapiens 116-125 7246736-2 1981 PRL secretion over 4 h was inhibited comparably by 10(-6) M dopamine (DA), 10(-7) M apomorphine (APO), and 10(-10) M bromocriptine (45%, 42%, 51%, respectively) with reciprocal increases in intracellular hormone content. Apomorphine 84-95 prolactin Homo sapiens 0-3 7246736-2 1981 PRL secretion over 4 h was inhibited comparably by 10(-6) M dopamine (DA), 10(-7) M apomorphine (APO), and 10(-10) M bromocriptine (45%, 42%, 51%, respectively) with reciprocal increases in intracellular hormone content. Apomorphine 97-100 prolactin Homo sapiens 0-3 6403331-8 1983 The dopamine agonist apomorphine (100 micrograms/kg, iv) induced a similar suppression of fetal PRL concentrations in CON (n = 4) and SS (n = 2) fetuses. Apomorphine 21-32 prolactin Homo sapiens 96-99 6812112-2 1982 Apomorphine chloride (AP) (0.18-0.24 mg IV) induced stimulation of growth hormone (GH) and suppression of prolactin (PRL), as shown 2-3 days before and after ECT in mentally depressed patients (N = 12) and therapy-resistant parkinsonian patients with on-off phenomena (N = 9). Apomorphine 0-20 prolactin Homo sapiens 106-115 6812112-2 1982 Apomorphine chloride (AP) (0.18-0.24 mg IV) induced stimulation of growth hormone (GH) and suppression of prolactin (PRL), as shown 2-3 days before and after ECT in mentally depressed patients (N = 12) and therapy-resistant parkinsonian patients with on-off phenomena (N = 9). Apomorphine 0-20 prolactin Homo sapiens 117-120 6120733-2 1981 Plasma growth hormone and prolactin responses to apomorphine. Apomorphine 49-60 prolactin Homo sapiens 26-35 6120733-9 1981 The absolute decline in plasma PRL following apomorphine correlated positively with the baseline PRL concentration and was unrelated to the daily doses of neuroleptics or to any other variable considered. Apomorphine 45-56 prolactin Homo sapiens 31-34 6120733-9 1981 The absolute decline in plasma PRL following apomorphine correlated positively with the baseline PRL concentration and was unrelated to the daily doses of neuroleptics or to any other variable considered. Apomorphine 45-56 prolactin Homo sapiens 97-100 7264625-7 1981 The effects of single doses of apomorphine, bromocriptine, lisuride and haloperidol, were studied on serum levels of PRL in 21 PP divided in two groups of "responders" and "non-responders". Apomorphine 31-42 prolactin Homo sapiens 117-120 7264625-8 1981 Haloperidol induced an enhancement of serum PRL; the dopaminergic drugs, apomorphine, bromocriptine and lisuride inhibited basal PRL secretion. Apomorphine 73-84 prolactin Homo sapiens 129-132 540209-1 1979 Apomorphine, a direct-acting dopamine agonist, stimulates release of growth hormone (hGH) and suppresses release of prolactin (PRL) from the anterior pituitary. Apomorphine 0-11 prolactin Homo sapiens 127-130 703603-0 1978 Effect of apomorphine and piribedil on the secretion of thyrotropin and prolactin in patients with primary hypothyroidism. Apomorphine 10-21 prolactin Homo sapiens 72-81 288372-3 1979 Dopaminergic agonists (apomorphine, piribedil, d-amphetamine, L-DOPA, and the ergot derivatives bromocriptine and lisuride) all caused a decrease of serum prolactin levels. Apomorphine 23-34 prolactin Homo sapiens 155-164 703603-1 1978 The administration of apomorphine and piribedil, two dopaminergic agents, significantly reduced thyrotropin (TSH) and prolactin levels in six female patients with primary hypothyroidism. Apomorphine 22-33 prolactin Homo sapiens 118-127 591612-1 1977 In 6 normal subjects, L-dopa (500 mg PO) and apomorphine (0.6 mg sc) increased circulating growth hormone and suppressed prolactin levels in a parallel and quantitatively similar fashion, but only L-dopa induced a rise in plasma glucagon, glucose, and insulin levels. Apomorphine 45-56 prolactin Homo sapiens 121-130 402381-1 1977 Pretreatment of normal subjects with apomorphine, a dopamine receptor agonist, resulted in significant impairment of the subsequent prolactin (PRL) response to thyrotropin releasing hormone (TRH). Apomorphine 37-48 prolactin Homo sapiens 133-142 1030132-0 1976 [Effect of apomorphine on the secretion of prolactin in florid acromegaly]. Apomorphine 11-22 prolactin Homo sapiens 43-52 13627-4 1976 Pharmacological agents such as apomorphine and many of the ergot alkaloids are very effective inhibitors of the secretion of prolactin. Apomorphine 31-42 prolactin Homo sapiens 125-134 1176587-2 1975 Apomorphine prevented the morphine induced prolactin rise. Apomorphine 0-11 prolactin Homo sapiens 43-52