PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 2122640-4 1990 These observations suggest that PLC activation by ATP involves a G-protein(s) that is not ADP-ribosylated by pertussis toxin and further, that ATP activation of prostaglandin biosynthesis appears to involve a different, pertussis toxin sensitive, G-protein. Adenosine Triphosphate 50-53 LOC100009319 Oryctolagus cuniculus 32-35 2293202-0 1990 Adenosine-5"-triphosphate-induced sinus tachycardia mediated by prostaglandin synthesis via phospholipase C in the rabbit heart. Adenosine Triphosphate 0-25 LOC100009319 Oryctolagus cuniculus 92-107 2122640-1 1990 ATP stimulates arachidonic acid release and prostaglandin biosynthesis (most likely via phospholipase A2 (PLA2) activation) and phospholipase C (PLC) activation in cultured rabbit coronary microvessel endothelial cells. Adenosine Triphosphate 0-3 LOC100009319 Oryctolagus cuniculus 145-148 9696270-8 1998 Although the elevations to ACh or ATP were abolished by neomycin (an inhibitor of phospholipase C) the different time courses suggest that the mechanisms of release of Ca2+ from intracellular stores or the pathway for refilling the stores is different. Adenosine Triphosphate 34-37 LOC100009319 Oryctolagus cuniculus 82-97 9178188-7 1997 Dexamethasone and indomethacin which potently inhibited ATP-induced PGE2 generation, caused partial inhibition of phosphoinositide hydrolysis, suggesting that pertussis toxin-sensitive component of ATP-induced phospholipase C activation is mediated by cyclo-oxygenase metabolites of arachidonic acid. Adenosine Triphosphate 198-201 LOC100009319 Oryctolagus cuniculus 210-225 6432054-2 1984 In cells prelabelled with 32Pi it would be expected that the newly synthesised phosphatidate would have the same specific activity as cellular ATP, provided that the loss of phosphatidylinositol is by phospholipase C attack and the resultant diacyglycerol is phosphorylated by ATP. Adenosine Triphosphate 143-146 LOC100009319 Oryctolagus cuniculus 201-216 10409228-6 1999 The ATP-induced Ca(2+) oscillations were abolished by the phospholipase C inhibitor U-73122 and by the endoplasmic reticulum Ca(2+)-pump inhibitor thapsigargin but were maintained in Ca(2+)-free medium. Adenosine Triphosphate 4-7 LOC100009319 Oryctolagus cuniculus 58-73 10805322-10 1999 In conclusion, the ATP-induced [Ca2+]i-elevation in the rabbit eye suprachoroid was elicited by the Ca2+ release from the PLC-dependent, thapsigargin-sensitive intracellular Ca2+ storage sites by activating P2Y2 nucleotide receptors. Adenosine Triphosphate 19-22 LOC100009319 Oryctolagus cuniculus 122-125