PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
14652635-6	2003	Following i.v.Ig treatment of HUVEC, the Ca(2+) liberation from internal stores and the vWf secretion induced by ATP, thrombin or histamine were significantly reduced by 38 and 60%, respectively.	Adenosine Triphosphate	113-116	von Willebrand factor	Homo sapiens	88-91	
30864273-14	2019	Lastly, under high shear stress VWF treated with FAM20c and ATP robustly supported platelet adhesion, compared to VWF treated with FAM20c in the absence of ATP.	Adenosine Triphosphate	60-63	von Willebrand factor	Homo sapiens	32-35	
15087444-0	2004	ATP augments von Willebrand factor-dependent shear-induced platelet aggregation through Ca2+-calmodulin and myosin light chain kinase activation.	Adenosine Triphosphate	0-3	von Willebrand factor	Homo sapiens	13-34	
9163596-2	1997	Platelets aggregated and released ATP in response to stirring with VWF beads.	Adenosine Triphosphate	34-37	von Willebrand factor	Homo sapiens	67-70	
11958804-4	2002	Oil treatment of platelets reduced the vWF bead-induced ATP release insignificantly.	Adenosine Triphosphate	56-59	von Willebrand factor	Homo sapiens	39-42	
11341505-7	2001	In addition, both the anti-GPIb MoAb 9C8, or the two anti-vWF MoAbs 1C1E7 and B724 induce genuine platelet activation, as evidenced by the secretion of ATP and protein tyrosine phosphorylation.	Adenosine Triphosphate	152-155	von Willebrand factor	Homo sapiens	58-61	
9414275-6	1998	ATP (1 to 100 micromol/L) induced a dose-related increase in vWF release, with a 2.3-fold maximal increase after 30 minutes.	Adenosine Triphosphate	0-3	von Willebrand factor	Homo sapiens	61-64	
9414275-9	1998	However, 2-methylthio-ATP-induced vWF release was only 43% of the ATP response.	Adenosine Triphosphate	22-25	von Willebrand factor	Homo sapiens	34-37	
9414275-10	1998	ATP-induced vWF release was also associated with a twofold increase in cellular cyclic adenosine monophosphate (cAMP) content, and was potentiated by 3-isobutyl-1-methylxanthine ([IBMX] added to increase cAMP levels by blocking cellular phosphodiesterases) and 8-bromo-cAMP and inhibited by more than 50% by Rp-8-CPT-cAMPS, a competitive protein kinase A inhibitor.	Adenosine Triphosphate	0-3	von Willebrand factor	Homo sapiens	12-15	
9414275-12	1998	ATP-induced vWF release was partly inhibited by adenosine deaminase, which degrades adenosine generated from ATP in the incubation medium.	Adenosine Triphosphate	0-3	von Willebrand factor	Homo sapiens	12-15	
9414275-12	1998	ATP-induced vWF release was partly inhibited by adenosine deaminase, which degrades adenosine generated from ATP in the incubation medium.	Adenosine Triphosphate	109-112	von Willebrand factor	Homo sapiens	12-15	
9414275-14	1998	Our results suggest that ATP/ADP can induce vWF release from endothelial cells via dual activation of P2y and adenosine A2 receptors.	Adenosine Triphosphate	25-28	von Willebrand factor	Homo sapiens	44-47	
9390640-2	1997	We found that platelet-vWf expression on the surfaces of both unstimulated and stimulated platelets required energy and was maximally decreased when metabolic ATP was maximally depleted.	Adenosine Triphosphate	159-162	von Willebrand factor	Homo sapiens	23-26	
9163596-8	1997	12 patients were abnormal by conventional optical aggregometry, whereas 27 patients showed depressed ATP release in response to VWF beads.	Adenosine Triphosphate	101-104	von Willebrand factor	Homo sapiens	128-131	
8883288-2	1996	The present report shows that prostacyclin and nitroprusside, vasodilator-compounds that enhance the cAMP and cGMP concentration respectively, cause a drastic inhibition of the type IIB vWF-induced platelet responses including increase of cytosolic Ca2+ concentration, phosphorylation of pleckstrin (47 kDa) and myosin light chain (20 kDa), secretion of ATP and serotonin, and aggregation parallel to a decrease of arachidonic acid release.	Adenosine Triphosphate	354-357	von Willebrand factor	Homo sapiens	186-189	
7974361-4	1994	We have examined the effects of the platelet secretagogues ADP, AMP, ATP and serotonin on the release of vWf from ECs and demonstrated enhanced release in all cases.	Adenosine Triphosphate	69-72	von Willebrand factor	Homo sapiens	105-108	
3118988-8	1987	Both thromboxane B2 formation and adenosine triphosphate secretion showed an AS-vWF concentration dependence paralleling the aggregation responses.	Adenosine Triphosphate	34-56	von Willebrand factor	Homo sapiens	80-83	
7669029-4	1995	ATP secretion and platelet aggregation also occurred with type IIB vWF concentrations higher than about 5 micrograms/ml, which corresponds to the original plasmatic level.	Adenosine Triphosphate	0-3	von Willebrand factor	Homo sapiens	67-70