PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33529751-0	2021	Diphenyleneiodonium enhances P2X7 dependent non - opsonized phagocytosis and suppresses inflammasome activation via blocking CX43 - mediated ATP leakage.	Adenosine Triphosphate	141-144	gap junction protein, alpha 3	Mus musculus	125-129	
33529751-6	2021	Mechanistically, DPI upregulated p38 MAPK phosphorylation to suppress the expression and activity of the hemichannel protein connexin 43 (CX43), leading to the inhibition of CX43-mediated ATP efflux in E. coli-infected macrophages.	Adenosine Triphosphate	188-191	gap junction protein, alpha 3	Mus musculus	138-142	
33529751-6	2021	Mechanistically, DPI upregulated p38 MAPK phosphorylation to suppress the expression and activity of the hemichannel protein connexin 43 (CX43), leading to the inhibition of CX43-mediated ATP efflux in E. coli-infected macrophages.	Adenosine Triphosphate	188-191	gap junction protein, alpha 3	Mus musculus	174-178	
33529751-8	2021	In summary, our study demonstrates a previously unknown function of DPI in conferring protection against bacterial infection and suggests a putative antimicrobial strategy of modulating CX43 -dependent ATP leakage.	Adenosine Triphosphate	202-205	gap junction protein, alpha 3	Mus musculus	186-190	
32450899-11	2020	CONCLUSION: Data suggest that Cx43 mediated ATP release represents an initial trigger in early tubular injury via its actions on the adherens and tight junction complex.	Adenosine Triphosphate	44-47	gap junction protein, alpha 3	Mus musculus	30-34	
24578339-11	2014	In conclusion, our results have suggested novel roles of basal activation of CD38/cADPR-dependent signaling in mediating microglial functions and survival: It mediates ATP release from microglia by modulating Cx43 hemichannels, which can significantly affect microglial survival.	Adenosine Triphosphate	168-171	gap junction protein, alpha 3	Mus musculus	209-213	
22399755-4	2012	In vivo bioluminescence imaging showed a significant reduction in ATP release after weight-drop injury in mice with deletion of Cx43 compared with Cx43-expressing littermates, both on a Cx30 knockout background.	Adenosine Triphosphate	66-69	gap junction protein, alpha 3	Mus musculus	128-132	
27041582-7	2016	These inhibitory effects on cancer cells were mediated by ATP released from osteocyte Cx43 hemichannels.	Adenosine Triphosphate	58-61	gap junction protein, alpha 3	Mus musculus	86-90	
24578339-6	2014	Cx43 small interfering RNA and Cx43 hemichannel blocker 18-alpha-glycyrrhetinic acid completely prevented the CD38 silencing or 8-Bromo-cADPR-induced ATP release.	Adenosine Triphosphate	150-153	gap junction protein, alpha 3	Mus musculus	0-4	
24578339-6	2014	Cx43 small interfering RNA and Cx43 hemichannel blocker 18-alpha-glycyrrhetinic acid completely prevented the CD38 silencing or 8-Bromo-cADPR-induced ATP release.	Adenosine Triphosphate	150-153	gap junction protein, alpha 3	Mus musculus	31-35