PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17463068-2 2007 UCP2 is a member of the mitochondrial proton transport family, which uncouples proton entry in the mitochondrial matrix from ATP synthesis. Adenosine Triphosphate 125-128 uncoupling protein 2 Homo sapiens 0-4 17855623-1 2008 Uncoupling protein-2 (UCP2) belongs to the mitochondrial carrier family and has been thought to be involved in suppressing mitochondrial ROS production through uncoupling mitochondrial respiration from ATP synthesis. Adenosine Triphosphate 202-205 uncoupling protein 2 Homo sapiens 0-20 17855623-1 2008 Uncoupling protein-2 (UCP2) belongs to the mitochondrial carrier family and has been thought to be involved in suppressing mitochondrial ROS production through uncoupling mitochondrial respiration from ATP synthesis. Adenosine Triphosphate 202-205 uncoupling protein 2 Homo sapiens 22-26 15937145-1 2005 Uncoupling protein 2 (UCP-2) regulates mitochondrial function by increasing proton leak across the inner membrane to dissociate respiration from ATP synthesis and reduce reactive oxygen species generation. Adenosine Triphosphate 145-148 uncoupling protein 2 Homo sapiens 0-20 16580138-8 2006 We also found that exercise significantly increased the expression of the mitochondrial uncoupling protein 2, an energy-balancing factor concerned with ATP production and free radical management. Adenosine Triphosphate 152-155 uncoupling protein 2 Homo sapiens 74-108 16982633-3 2007 Uncoupling protein 2 (UCP2) uncouples respiration from ATP synthesis, thus regulating energy expenditure and fat oxidation. Adenosine Triphosphate 55-58 uncoupling protein 2 Homo sapiens 0-20 16982633-3 2007 Uncoupling protein 2 (UCP2) uncouples respiration from ATP synthesis, thus regulating energy expenditure and fat oxidation. Adenosine Triphosphate 55-58 uncoupling protein 2 Homo sapiens 22-26 16021520-1 2005 Uncoupling protein 2 (UCP2) is a member of the mitochondrial proton transport family that uncouples proton entry to the mitochondria from ATP synthesis. Adenosine Triphosphate 138-141 uncoupling protein 2 Homo sapiens 0-20 16021520-1 2005 Uncoupling protein 2 (UCP2) is a member of the mitochondrial proton transport family that uncouples proton entry to the mitochondria from ATP synthesis. Adenosine Triphosphate 138-141 uncoupling protein 2 Homo sapiens 22-26 15937145-1 2005 Uncoupling protein 2 (UCP-2) regulates mitochondrial function by increasing proton leak across the inner membrane to dissociate respiration from ATP synthesis and reduce reactive oxygen species generation. Adenosine Triphosphate 145-148 uncoupling protein 2 Homo sapiens 22-27 15654602-9 2005 In particular, UCP-2 expression is increased (probably due to a condition of fuel overload), which leads to lower ATP, decreased ATP/ADP ratio, with consequent reduction of insulin release. Adenosine Triphosphate 114-117 uncoupling protein 2 Homo sapiens 15-20 15654602-9 2005 In particular, UCP-2 expression is increased (probably due to a condition of fuel overload), which leads to lower ATP, decreased ATP/ADP ratio, with consequent reduction of insulin release. Adenosine Triphosphate 129-132 uncoupling protein 2 Homo sapiens 15-20 15220218-1 2004 Uncoupling protein (UCP)-2 is a member of the mitochondrial inner membrane carriers that uncouple pro-ton entry in the mitochondrial matrix from ATP synthesis. Adenosine Triphosphate 145-148 uncoupling protein 2 Homo sapiens 0-26 16075814-7 2005 On the other hand, the uncoupling induced by UCP2 in mitochondria of pancreatic beta cells decreases ATP synthesis and impairs insulin secretion in response to glucose. Adenosine Triphosphate 101-104 uncoupling protein 2 Homo sapiens 45-49 15322095-9 2004 In addition, we further demonstrate that the dissipation of DeltaPsim is accompanied by significant reduction of cellular ATP in 293T cells overexpressing HDMCP or uncoupling protein 2 (UCP2). Adenosine Triphosphate 122-125 uncoupling protein 2 Homo sapiens 164-184 15322095-9 2004 In addition, we further demonstrate that the dissipation of DeltaPsim is accompanied by significant reduction of cellular ATP in 293T cells overexpressing HDMCP or uncoupling protein 2 (UCP2). Adenosine Triphosphate 122-125 uncoupling protein 2 Homo sapiens 186-190 15599605-2 2005 This review focuses on transmitter-receptor mismatches in the brain, which is one of the hallmarks of the Volume Transmission (VT) concept, and how this phenomenon may be related to local temperature gradients created by brain uncoupling protein 2 (UCP2), which uncouples oxidative phosphorylation from ATP synthesis, hereby generating heat. Adenosine Triphosphate 303-306 uncoupling protein 2 Homo sapiens 227-247 14679178-3 2003 Uncoupling protein 2 (UCP2), by virtue of its mitochondrial proton leak activity and consequent negative effect on ATP production, impairs glucose-stimulated insulin secretion. Adenosine Triphosphate 115-118 uncoupling protein 2 Homo sapiens 0-20 14693721-1 2004 Uncoupling protein (UCP) 2 is a member of the mitochondrial transporter superfamily that uncouples proton entry in the mitochondrial matrix from ATP synthesis. Adenosine Triphosphate 145-148 uncoupling protein 2 Homo sapiens 0-26 14679173-3 2003 A new study demonstrates that hyperglycemia-induced mitochondrial superoxide production activates uncoupling protein 2, which decreases the ATP/ADP ratio and thus reduces the insulin-secretory response. Adenosine Triphosphate 140-143 uncoupling protein 2 Homo sapiens 98-118 14679178-3 2003 Uncoupling protein 2 (UCP2), by virtue of its mitochondrial proton leak activity and consequent negative effect on ATP production, impairs glucose-stimulated insulin secretion. Adenosine Triphosphate 115-118 uncoupling protein 2 Homo sapiens 22-26 14679178-6 2003 This study demonstrates that endogenously produced mitochondrial superoxide activates UCP2-mediated proton leak, thus lowering ATP levels and impairing glucose-stimulated insulin secretion. Adenosine Triphosphate 127-130 uncoupling protein 2 Homo sapiens 86-90 12011039-3 2002 We demonstrate in HeLa cells but not in normal diploid fibroblasts that modest increases in the expression level of uncoupling protein 2 (UCP-2) leads to a rapid and dramatic fall in mitochondrial membrane potential and to a reduction of mitochondrial NADH and intracellular ATP. Adenosine Triphosphate 275-278 uncoupling protein 2 Homo sapiens 116-136 12734183-4 2003 The Ki values for ATP inhibition were 50 microm (UCP1), 70 microm (UCP2), and 120 microm (UCP3) at pH 7.2. Adenosine Triphosphate 18-21 uncoupling protein 2 Homo sapiens 67-71 12011039-3 2002 We demonstrate in HeLa cells but not in normal diploid fibroblasts that modest increases in the expression level of uncoupling protein 2 (UCP-2) leads to a rapid and dramatic fall in mitochondrial membrane potential and to a reduction of mitochondrial NADH and intracellular ATP. Adenosine Triphosphate 275-278 uncoupling protein 2 Homo sapiens 138-143 12418549-4 2002 We have confirmed that ATP and GTP inhibit such FA-induced H+ uniport mediated by UCP2 and UCP3. Adenosine Triphosphate 23-26 uncoupling protein 2 Homo sapiens 82-86 11098051-1 2001 Uncoupling protein 2 (UCP2) belongs to the mitochondrial anion carrier family and partially uncouples respiration from ATP synthesis when expressed in recombinant yeast mitochondria. Adenosine Triphosphate 119-122 uncoupling protein 2 Homo sapiens 0-20 11929192-7 2002 While UCP1 has a clear role in energy homeostasis, the newcomers UCP2-UCP5 may have more delicate physiological importance acting as free radical oxygen scavengers and in the regulation of ATP-dependent processes, such as secretion. Adenosine Triphosphate 189-192 uncoupling protein 2 Homo sapiens 65-69 11381268-3 2001 Like its close relatives UCP1 and UCP3, UCP2 uncouples proton entry in the mitochondrial matrix from ATP synthesis and is therefore a candidate gene for obesity. Adenosine Triphosphate 101-104 uncoupling protein 2 Homo sapiens 40-44 10023736-1 1999 Uncoupling protein (UCP) 2 and UCP3 are newly discovered proteins that can uncouple ATP production from mitochondrial respiration, thereby dissipating energy as heat and affecting energy metabolism efficiency. Adenosine Triphosphate 84-87 uncoupling protein 2 Homo sapiens 0-26 11171965-9 2001 In UCP2 as in UCP1, ATP is a stronger inhibitor than ADP, but in UCP3 ADP inhibits more strongly than ATP. Adenosine Triphosphate 20-23 uncoupling protein 2 Homo sapiens 3-7 11179956-11 2001 The EPR data show large structural changes in UCP1 and UCP2 on exposure to ATP, implying that a putative nucleotide-binding site is present on UCP2. Adenosine Triphosphate 75-78 uncoupling protein 2 Homo sapiens 55-59 11179956-11 2001 The EPR data show large structural changes in UCP1 and UCP2 on exposure to ATP, implying that a putative nucleotide-binding site is present on UCP2. Adenosine Triphosphate 75-78 uncoupling protein 2 Homo sapiens 143-147 10454128-1 1999 Uncoupling protein-2 (UCP2) and uncoupling protein-3 (UCP3) are mitochondrial proteins that may play a role in the control of energy expenditure by uncoupling respiration from ATP synthesis. Adenosine Triphosphate 176-179 uncoupling protein 2 Homo sapiens 0-20 10454128-1 1999 Uncoupling protein-2 (UCP2) and uncoupling protein-3 (UCP3) are mitochondrial proteins that may play a role in the control of energy expenditure by uncoupling respiration from ATP synthesis. Adenosine Triphosphate 176-179 uncoupling protein 2 Homo sapiens 22-26 35091061-7 2022 Live-cell imaging revealed that T3-induced enhancement of mitochondrial Ca2+ uptake depends on the mitochondrial Ca2+ uniporter (MCU), UCP2, and PRMT1 that are essential for increased mitochondrial ATP ((ATP)mito) production after T3 treatment. Adenosine Triphosphate 198-201 uncoupling protein 2 Homo sapiens 135-139 9661627-2 1998 By uncoupling respiration from ATP synthesis, UCP2 might be involved in the control of energy expenditure. Adenosine Triphosphate 31-34 uncoupling protein 2 Homo sapiens 46-50 35091061-7 2022 Live-cell imaging revealed that T3-induced enhancement of mitochondrial Ca2+ uptake depends on the mitochondrial Ca2+ uniporter (MCU), UCP2, and PRMT1 that are essential for increased mitochondrial ATP ((ATP)mito) production after T3 treatment. Adenosine Triphosphate 204-207 uncoupling protein 2 Homo sapiens 135-139 35091061-10 2022 Based on these results, we assume that thyroid hormones adjust (Ca2+)mito homeostasis by modulating the UCP2- and PRMT1-balanced (Ca2+)mito uptake via MCU in case of physiological ROS levels to convey their impact on mitochondrial ATP and ROS production. Adenosine Triphosphate 231-234 uncoupling protein 2 Homo sapiens 104-108 33530558-2 2021 In this work, we use a combination of homology modelling and subsequent microsecond molecular dynamics simulations of UCP2 in the DOPC phospholipid bilayer, starting from the structure of the mitochondrial ATP/ADP carrier (ANT) as a template. Adenosine Triphosphate 206-209 uncoupling protein 2 Homo sapiens 118-122 33530558-4 2021 We also show that ATP binding in the UCP2 cavity is tight in the homology modelled structure of UCP2 in agreement with experimental observations. Adenosine Triphosphate 18-21 uncoupling protein 2 Homo sapiens 37-41 33530558-4 2021 We also show that ATP binding in the UCP2 cavity is tight in the homology modelled structure of UCP2 in agreement with experimental observations. Adenosine Triphosphate 18-21 uncoupling protein 2 Homo sapiens 96-100 30160798-2 2018 UCP2 is a mitochondrial carrier protein that creates proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation from adenosine triphosphate (ATP) synthesis. Adenosine Triphosphate 154-176 uncoupling protein 2 Homo sapiens 0-4 30952098-8 2019 In vitro, UCP2 overexpression protected HK-2 cells from LPS-induced injury by suppression of apoptosis, inflammation, oxidative stress, MMP loss and ROS production, increase of ATP production and mtDNA content, and amelioration of damage to the mitochondrial ultrastructure. Adenosine Triphosphate 177-180 uncoupling protein 2 Homo sapiens 10-14 30538804-8 2018 The beta3-AR/UCP2 axis induces a strong reduction of mitochondrial activity by reducing ATP synthesis and mitochondrial reactive oxygen species (mtROS) content. Adenosine Triphosphate 88-91 uncoupling protein 2 Homo sapiens 13-17 31771728-15 2019 (4) The results of immunofluorescence showed that the ATP content of CLP group and AAV group were significantly lower than that of Sham group; the ATP content of UCP2 group was significantly higher than that of CLP group and AAV group (mumol/L: 1.99+-0.15 vs. 1.10+-0.17, 1.13+-0.19, both P < 0.05). Adenosine Triphosphate 147-150 uncoupling protein 2 Homo sapiens 162-166 30995317-9 2019 Compared to control, treatment with genipin or knockdown of UCP2 significantly increased Glut1, glucose uptake, ATP production, VEGF-induced p-VEGFR2 and cell proliferation in hRMVECs. Adenosine Triphosphate 112-115 uncoupling protein 2 Homo sapiens 60-64 30160798-2 2018 UCP2 is a mitochondrial carrier protein that creates proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation from adenosine triphosphate (ATP) synthesis. Adenosine Triphosphate 178-181 uncoupling protein 2 Homo sapiens 0-4 28737710-5 2017 Uncoupling protein 2 (UCP2) regulates ATP (Adenosine triphosphate) and reactive oxygen species production by affecting the mitochondrial respiratory chain, which may play a protective role in CIR. Adenosine Triphosphate 38-41 uncoupling protein 2 Homo sapiens 0-20 28771482-1 2017 Uncoupling protein 2 (UCP2) is a mitochondrial membrane protein that plays a role in uncoupling electron transport from adenosine triphosphate (ATP) formation. Adenosine Triphosphate 144-147 uncoupling protein 2 Homo sapiens 0-20 28771482-1 2017 Uncoupling protein 2 (UCP2) is a mitochondrial membrane protein that plays a role in uncoupling electron transport from adenosine triphosphate (ATP) formation. Adenosine Triphosphate 144-147 uncoupling protein 2 Homo sapiens 22-26 29254145-9 2017 Furthermore, over-expression of UCP2 abrogated DCA and CSC-mediated increases in lactate and ATP production in EACC. Adenosine Triphosphate 93-96 uncoupling protein 2 Homo sapiens 32-36 28737710-5 2017 Uncoupling protein 2 (UCP2) regulates ATP (Adenosine triphosphate) and reactive oxygen species production by affecting the mitochondrial respiratory chain, which may play a protective role in CIR. Adenosine Triphosphate 38-41 uncoupling protein 2 Homo sapiens 22-26 28737710-5 2017 Uncoupling protein 2 (UCP2) regulates ATP (Adenosine triphosphate) and reactive oxygen species production by affecting the mitochondrial respiratory chain, which may play a protective role in CIR. Adenosine Triphosphate 43-65 uncoupling protein 2 Homo sapiens 0-20 28737710-5 2017 Uncoupling protein 2 (UCP2) regulates ATP (Adenosine triphosphate) and reactive oxygen species production by affecting the mitochondrial respiratory chain, which may play a protective role in CIR. Adenosine Triphosphate 43-65 uncoupling protein 2 Homo sapiens 22-26 24395786-5 2014 Compared with wild-type, UCP2-silenced human hepatocellular carcinoma (HepG2) cells, grown in the presence of glucose, showed a higher inner mitochondrial membrane potential and ATP:ADP ratio associated with a lower lactate release. Adenosine Triphosphate 178-181 uncoupling protein 2 Homo sapiens 25-29 25789405-1 2015 Residing at the inner mitochondrial membrane, uncoupling protein-2 (UCP2) mediates proton transport from the intermembrane space (IMS) to the mitochondrial matrix and consequently reduces the rate of ATP synthesis in the mitochondria. Adenosine Triphosphate 200-203 uncoupling protein 2 Homo sapiens 46-66 25789405-1 2015 Residing at the inner mitochondrial membrane, uncoupling protein-2 (UCP2) mediates proton transport from the intermembrane space (IMS) to the mitochondrial matrix and consequently reduces the rate of ATP synthesis in the mitochondria. Adenosine Triphosphate 200-203 uncoupling protein 2 Homo sapiens 68-72 25256770-1 2014 Uncoupling protein 2 (UCP2) is a mitochondrial anion carrier protein, which uncouples the oxidative phosphorylation from ATP production by dissipating the proton gradient generated across the mitochondrial inner membrane. Adenosine Triphosphate 121-124 uncoupling protein 2 Homo sapiens 0-20 25256770-1 2014 Uncoupling protein 2 (UCP2) is a mitochondrial anion carrier protein, which uncouples the oxidative phosphorylation from ATP production by dissipating the proton gradient generated across the mitochondrial inner membrane. Adenosine Triphosphate 121-124 uncoupling protein 2 Homo sapiens 22-26 25256770-2 2014 UCP2 regulates not only mitochondrial ATP production, but also the generation of reactive oxygen species (ROS), considered important second-messenger signals within the cell. Adenosine Triphosphate 38-41 uncoupling protein 2 Homo sapiens 0-4 24294945-6 2014 Moreover, activation of the transcription factor peroxisome proliferator-activated receptor alpha induces expression of mitochondrial uncoupling protein 2, resulting in depletion of cellular energy (ATP) reserves. Adenosine Triphosphate 199-202 uncoupling protein 2 Homo sapiens 120-154 26739488-6 2016 Our results indicate that this abnormality is associated with a decrease in ATP production due to the elevated expression of mitochondrial uncoupling protein 2 (UCP2). Adenosine Triphosphate 76-79 uncoupling protein 2 Homo sapiens 125-159 26739488-6 2016 Our results indicate that this abnormality is associated with a decrease in ATP production due to the elevated expression of mitochondrial uncoupling protein 2 (UCP2). Adenosine Triphosphate 76-79 uncoupling protein 2 Homo sapiens 161-165 23505621-1 2013 Uncoupling proteins 2 and 3 (UCP2 and UCP3) as mitochondrial electron transporters are involved in regulation of ATP production and energy dissipation as heat. Adenosine Triphosphate 113-116 uncoupling protein 2 Homo sapiens 0-27 22349573-1 2013 CONTEXT: Uncoupling protein 2 (UCP2) is involved in regulating ATP synthesis, generation of reactive oxygen species and glucose-stimulated insulin secretion in beta-cells. Adenosine Triphosphate 63-66 uncoupling protein 2 Homo sapiens 9-29 22349573-1 2013 CONTEXT: Uncoupling protein 2 (UCP2) is involved in regulating ATP synthesis, generation of reactive oxygen species and glucose-stimulated insulin secretion in beta-cells. Adenosine Triphosphate 63-66 uncoupling protein 2 Homo sapiens 31-35 23505621-1 2013 Uncoupling proteins 2 and 3 (UCP2 and UCP3) as mitochondrial electron transporters are involved in regulation of ATP production and energy dissipation as heat. Adenosine Triphosphate 113-116 uncoupling protein 2 Homo sapiens 29-33 22266335-5 2012 Under normal conditions, hUCP2 flies maintain an enhanced locomotor activity and have higher steady-state ATP levels suggesting improved energy homeostasis. Adenosine Triphosphate 106-109 uncoupling protein 2 Homo sapiens 25-30 24440978-1 2013 BACKGROUND: Mitochondrial uncoupling protein 2 (UCP2) uncouples electron transport from ATP production. Adenosine Triphosphate 88-91 uncoupling protein 2 Homo sapiens 12-46 24440978-1 2013 BACKGROUND: Mitochondrial uncoupling protein 2 (UCP2) uncouples electron transport from ATP production. Adenosine Triphosphate 88-91 uncoupling protein 2 Homo sapiens 48-52 22241057-1 2012 Uncoupling proteins 2 and 3 (UCP2 and UCP3) may negatively regulate mitochondrial ATP synthesis and, through this, influence human physical performance. Adenosine Triphosphate 82-85 uncoupling protein 2 Homo sapiens 0-27 22241057-1 2012 Uncoupling proteins 2 and 3 (UCP2 and UCP3) may negatively regulate mitochondrial ATP synthesis and, through this, influence human physical performance. Adenosine Triphosphate 82-85 uncoupling protein 2 Homo sapiens 29-33 22266335-7 2012 Those results suggest that it is increased mitochondrial function but not mitochondrial biogenesis that appears responsible for higher ATP levels in hUCP2 flies. Adenosine Triphosphate 135-138 uncoupling protein 2 Homo sapiens 149-154 22110477-5 2012 ROS activate UCP2, which results in proton leak across the mitochondrial inner membrane, and this leads to reduced beta-cell ATP synthesis and content, which is a critical parameter in regulating glucose-stimulated insulin secretion. Adenosine Triphosphate 125-128 uncoupling protein 2 Homo sapiens 13-17 22414059-5 2012 In addition, ROS activate UCP2 via peroxidation of the mitochondrial membrane phospholipids, which results in proton leak leading to reduced ATP synthesis and content in beta-cells - critical parameters in the regulation of glucose-stimulated insulin secretion. Adenosine Triphosphate 141-144 uncoupling protein 2 Homo sapiens 26-30 19272350-3 2009 In this study, UCP2 was inhibited by genipin in 3T3-L1 adipocytes, which increased mitochondrial membrane potential, intracellular ATP level and production of reactive oxygen species (ROS). Adenosine Triphosphate 131-134 uncoupling protein 2 Homo sapiens 15-19 22134120-1 2012 Uncoupling protein 2 (UCP2) is a mitochondrial transporter present in the inner membrane of mitochondria, and it uncouples substrate oxidation from ATP synthesis, thereby dissipating the membrane potential energy and consequently decreasing ATP production by mitochondrial respiratory chain. Adenosine Triphosphate 148-151 uncoupling protein 2 Homo sapiens 0-20 22134120-1 2012 Uncoupling protein 2 (UCP2) is a mitochondrial transporter present in the inner membrane of mitochondria, and it uncouples substrate oxidation from ATP synthesis, thereby dissipating the membrane potential energy and consequently decreasing ATP production by mitochondrial respiratory chain. Adenosine Triphosphate 148-151 uncoupling protein 2 Homo sapiens 22-26 22134120-1 2012 Uncoupling protein 2 (UCP2) is a mitochondrial transporter present in the inner membrane of mitochondria, and it uncouples substrate oxidation from ATP synthesis, thereby dissipating the membrane potential energy and consequently decreasing ATP production by mitochondrial respiratory chain. Adenosine Triphosphate 241-244 uncoupling protein 2 Homo sapiens 0-20 22134120-1 2012 Uncoupling protein 2 (UCP2) is a mitochondrial transporter present in the inner membrane of mitochondria, and it uncouples substrate oxidation from ATP synthesis, thereby dissipating the membrane potential energy and consequently decreasing ATP production by mitochondrial respiratory chain. Adenosine Triphosphate 241-244 uncoupling protein 2 Homo sapiens 22-26 19763737-7 2010 Stable knockdown of UCP2 expression reduced ATP levels, and abolished leptin protection against MPP+-induced mitochondrial depolarization, ATP deficiency, and cell death, indicating that UCP2 is critical in mediating these neuroprotective effects of leptin against MPP+ toxicity. Adenosine Triphosphate 44-47 uncoupling protein 2 Homo sapiens 20-24 19763737-7 2010 Stable knockdown of UCP2 expression reduced ATP levels, and abolished leptin protection against MPP+-induced mitochondrial depolarization, ATP deficiency, and cell death, indicating that UCP2 is critical in mediating these neuroprotective effects of leptin against MPP+ toxicity. Adenosine Triphosphate 139-142 uncoupling protein 2 Homo sapiens 20-24 19763737-9 2010 Our findings show that leptin preserves cell survival by maintaining MMP and ATP levels mediated through UCP2 in MPP+-induced toxicity. Adenosine Triphosphate 77-80 uncoupling protein 2 Homo sapiens 105-109 20056920-3 2010 However, in apparent conflict with its uncoupling role, UCP2 has also been proposed to be essential for mitochondrial Ca(2+) uptake, which could have a protective action by stimulating mitochondrial ATP production. Adenosine Triphosphate 199-202 uncoupling protein 2 Homo sapiens 56-60 20056920-5 2010 METHODS AND RESULTS: Adenoviral-mediated expression of UCP2 caused a mild depression of DeltaPsi(m) and increased the basal rate of oxygen consumption but did not affect total cellular ATP levels. Adenosine Triphosphate 185-188 uncoupling protein 2 Homo sapiens 55-59