PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27471616-7 2016 Measures designed to compensate for deficient ATP and HMGB1 signaling restored the chemotherapeutic response of Rip3 (-/-) and Mlkl (-/-) cancers. Adenosine Triphosphate 46-49 mixed lineage kinase domain-like Mus musculus 127-131 32123582-6 2020 Based on specific chemical descriptors, 110 compounds proceeded into the secondary screening cascade, which then identified seven compounds with maximum ability to reduce MLKL activation, IC50 >100 muM, EC50 2.5-11.5 muM under long-term necroptosis execution in murine fibroblast L929 cells, and full protection from ATP depletion and membrane leakage in human and murine cells. Adenosine Triphosphate 317-320 mixed lineage kinase domain-like Mus musculus 171-175