PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23132493-1 2013 Human CD1b molecules contain a maze of hydrophobic pockets and a tunnel capable of accommodating the unusually long, branched acyl chain of mycolic acids, an essential fatty acid component of the cell wall of mycobacteria. Mycolic Acids 140-153 CD1b molecule Homo sapiens 6-10 26652001-4 2015 To overcome the challenge, we generated mice that expressed human group 1 CD1 molecules (hCD1Tg) and a CD1b-restricted, mycolic-acid specific TCR (DN1Tg). Mycolic Acids 120-132 CD1b molecule Homo sapiens 103-107 23132493-2 2013 It has been accepted that CD1b-bound mycolic acids constitute a scaffold for mycolate-containing (glyco)lipids stimulating CD1b-restricted T cells. Mycolic Acids 37-50 CD1b molecule Homo sapiens 26-30 23132493-2 2013 It has been accepted that CD1b-bound mycolic acids constitute a scaffold for mycolate-containing (glyco)lipids stimulating CD1b-restricted T cells. Mycolic Acids 37-50 CD1b molecule Homo sapiens 123-127 23132493-3 2013 Remarkable homology in amino acid sequence is observed between human and monkey CD1b molecules, and indeed, monkey CD1b molecules are able to bind glucose monomycolate (GMM), a glucosylated species of mycolic acids, and present it to specific human T cells in vitro. Mycolic Acids 201-214 CD1b molecule Homo sapiens 80-84 23132493-3 2013 Remarkable homology in amino acid sequence is observed between human and monkey CD1b molecules, and indeed, monkey CD1b molecules are able to bind glucose monomycolate (GMM), a glucosylated species of mycolic acids, and present it to specific human T cells in vitro. Mycolic Acids 201-214 CD1b molecule Homo sapiens 115-119 30322965-6 2018 moDCs but not moLCs produced inflammatory cytokines after stimulation with CD1b and CD1d ligands mycolic acid and alpha-galactosylceramide, respectively. Mycolic Acids 97-109 CD1b molecule Homo sapiens 75-79 21576820-0 2011 A mycolic acid-specific CD1-restricted T cell population contributes to acute and memory immune responses in human tuberculosis infection. Mycolic Acids 2-14 CD1b molecule Homo sapiens 24-27 9219685-4 1997 The extreme hydrophobicity and shape of the binding site are consistent with observations that human CD1b and CD1c can present mycobacterial cell wall antigens, such as mycolic acid and lipoarabinomannans. Mycolic Acids 169-181 CD1b molecule Homo sapiens 101-105 32117314-5 2020 We found that CD1b tetramers loaded with mycolic acid or glucose monomycolate antigens stained TRAV1-2+ GEM T cells or TRBV4-1+ LDN5-like T cells in the majority of subjects tested, at rates ~10-fold lower than NKT cells. Mycolic Acids 41-53 CD1b molecule Homo sapiens 14-18 28665555-0 2017 CD1b-mycolic acid tetramers demonstrate T-cell fine specificity for mycobacterial lipid tails. Mycolic Acids 5-17 CD1b molecule Homo sapiens 0-4