PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
29887946-16	2018	Relative to the CDDP group, the CDDP+GSH group exhibited 47.92%, 47.82% and 63.75% downregulation in caspase3, caspase9 and bax mRNA expression, respectively, and a 2.17-fold increase in bcl-2 mRNA level.	cddp	32-36	BCL2 apoptosis regulator	Homo sapiens	187-192	
31077746-9	2019	Salinomycin abrogated nuclear translocation of NF-kappaB proteins and also caused a concurrent reduction in NF-kappaB regulated expression of pro-survival proteins e.g., survivin, XIAP and BCL-2 in CDDP-resistant cells.	cddp	198-202	BCL2 apoptosis regulator	Homo sapiens	189-194	
17022150-10	2005	There were significant correlations between the IC50 of CDDP and Bcl-2, BCRP, GST-pi, and between that of 5-FU and MRP 2.	cddp	56-60	BCL2 apoptosis regulator	Homo sapiens	65-70	
16170037-5	2005	The evaluation of molecular pathways involved in apoptosis indicates that the Bcl-2 but not the caspases may be involved in the CDDP protection of paclitaxel-induced apoptosis.	cddp	128-132	BCL2 apoptosis regulator	Homo sapiens	78-83	
15389812-11	2005	The differential induction of p21(WAF1/CIP1) and increase in Bax/Bcl-2 ratios with CDDP and DACH-Ac-Pt in LNCaP-LN3 cells appear to be linked to the relative activity of the two agents against this model.	cddp	83-87	BCL2 apoptosis regulator	Homo sapiens	65-70	
12012012-5	2002	Bcl-2 over-expression inhibited both delay in S-phase exit and CDDP-induced apoptosis in ATRA-pretreated cells.	cddp	63-67	BCL2 apoptosis regulator	Homo sapiens	0-5	
11819336-1	1998	AIM:To compare the expression level of Fas gene and Bcl-2 gene in gastric cancer cells SGC7901 and gastric cancer MDR (multidrug resistant) cells SGC7901/VCR,to transduce Fas cDNA and Bcl-2 antisense nucleic acid into SGC7901/VCR cells respectively, and to observe the expression of two genes in transfectants and non-transfectants as well as their drug sensitivity.METHODS:Eukaryotic expression vector pBK-Fas cDNA and pDOR-anti Bcl-2 were constructed and transfected into SGC7901/VCR cells by lipofectamine,respectively.Northern blot and Western blot were used to detect the expression of mRNA and protein in SGC7901/VCR and SGC7901 cells and transfectants, and drug sensitivity of transfectants for VCR, CDDP and 5-FU was analyzed with MTT assay.RESULTS:After gene transfection, 80 for Fas and 120 for antisense Bcl-2 drug-resistant clones were selected from 2 X10(5) cells, transfection rate being 0.04% and 0.06%.	cddp	707-711	BCL2 apoptosis regulator	Homo sapiens	52-57	
8476431-6	1993	Treatment with CDDP resulted in the same degree of DNA fragmentation in SBC-3 and SBC-3/Bcl2.	cddp	15-19	BCL2 apoptosis regulator	Homo sapiens	88-92	
24402872-10	2014	In contrast, CDDP-treated group showed a significant down regulation in the expression levels of Bcl-2 mRNA as compared to untreated control group.	cddp	13-17	BCL2 apoptosis regulator	Homo sapiens	97-102