PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
17988216-8	2008	Finally, the androgen metabolite androsterone, which is also an activator of FXR, dose-dependently reduces the glucuronidation of androgens catalysed by UGT2B15 and UGT2B17 in an FXR-dependent manner in LNCaP cells.	Androsterone	33-45	UDP glucuronosyltransferase family 2 member B17	Homo sapiens	165-172	
20628005-1	2010	UDP glucuronosyltransferase 2B17 is present in the prostate, where it catalyzes the addition of glucuronic acid to testosterone and dihydrotestosterone and their metabolites androsterone and androstane-3alpha,17beta-diol.	Androsterone	174-186	UDP glucuronosyltransferase family 2 member B17	Homo sapiens	0-32	
18471784-4	2008	Identification of the substrates for each member has revealed that three UGT2B enzymes are mainly responsible for DHT, ADT and 3alpha-DIOL glucuronidation: UGT2B7, UGT2B15 and UGT2B17.	Androsterone	119-122	UDP glucuronosyltransferase family 2 member B17	Homo sapiens	176-183	
19661211-5	2009	UGT2B17 readily glucuronidated androsterone and, particularly, etiocholanolone at the 3-OH, but in the two diols it exhibited high preference for the 17-OH and low glucuronidation rate at the 3-OH.	Androsterone	31-43	UDP glucuronosyltransferase family 2 member B17	Homo sapiens	0-7	
15666817-4	2004	We found that UGT2B17 is expressed in basal cells where DHEA is converted into 3alpha-DIOL and ADT.	Androsterone	95-98	UDP glucuronosyltransferase family 2 member B17	Homo sapiens	14-21	
11159850-11	2001	UGT2B15 and UGT2B17 showed similar glucuronidation activity for androstane-3alpha,17beta-diol (30% lower than that of UGT2B7), whereas UGT2B17 demonstrated the highest activity for androsterone, testosterone, and dihydrotestosterone.	Androsterone	181-193	UDP glucuronosyltransferase family 2 member B17	Homo sapiens	12-19	
11159850-11	2001	UGT2B15 and UGT2B17 showed similar glucuronidation activity for androstane-3alpha,17beta-diol (30% lower than that of UGT2B7), whereas UGT2B17 demonstrated the highest activity for androsterone, testosterone, and dihydrotestosterone.	Androsterone	181-193	UDP glucuronosyltransferase family 2 member B17	Homo sapiens	135-142	
10339403-7	1999	However, mutation of the serine residue at position 121 of UGT2B17 to a tyrosine, as found in UGT2B15, abolished the ability of UGT2B17 to conjugate androsterone at the 3alpha position, but still retained activity for dihydrotestosterone and 5alpha-androstane-3alpha, 17beta-diol, which have an OH-group at the 17beta position.	Androsterone	149-161	UDP glucuronosyltransferase family 2 member B17	Homo sapiens	59-66	
10339403-7	1999	However, mutation of the serine residue at position 121 of UGT2B17 to a tyrosine, as found in UGT2B15, abolished the ability of UGT2B17 to conjugate androsterone at the 3alpha position, but still retained activity for dihydrotestosterone and 5alpha-androstane-3alpha, 17beta-diol, which have an OH-group at the 17beta position.	Androsterone	149-161	UDP glucuronosyltransferase family 2 member B17	Homo sapiens	128-135	
9364925-1	1997	UGT2B17 is a UDP-glucuronosyltransferase enzyme expressed in several extrahepatic steroid target tissues, including the human prostate, where it glucuronidates C19 steroids such as dihydrotestosterone (DHT), androsterone (ADT), and androstane-3alpha, 17beta-diol (3alpha-diol).	Androsterone	208-220	UDP glucuronosyltransferase family 2 member B17	Homo sapiens	0-7	
9364925-1	1997	UGT2B17 is a UDP-glucuronosyltransferase enzyme expressed in several extrahepatic steroid target tissues, including the human prostate, where it glucuronidates C19 steroids such as dihydrotestosterone (DHT), androsterone (ADT), and androstane-3alpha, 17beta-diol (3alpha-diol).	Androsterone	222-225	UDP glucuronosyltransferase family 2 member B17	Homo sapiens	0-7	
11134149-8	2000	Using a specific anti-UGT2B17 antibody, the expression of this androsterone-conjugating UGT enzyme was found exclusively in basal cells of the epithelium.	Androsterone	63-75	UDP glucuronosyltransferase family 2 member B17	Homo sapiens	22-29	
8798464-10	1996	UGT2B17 is the first human uridine diphosphoglucuronosyltransferase enzyme expressed in extrahepatic tissues to have a specificity for ADT as well as testosterone, dihydrotestosterone, and 3alpha-diol.	Androsterone	135-138	UDP glucuronosyltransferase family 2 member B17	Homo sapiens	0-7