PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22837538-6	2012	At the cellular                     level, rapamycin decreases the number of myocytes with abnormal desmin                     accumulation and decreases the amount of desmin in both muscle and cardiac                     tissue of Lmna(-/-) mice.	Sirolimus	43-52	lamin A	Mus musculus	232-236	
29736257-8	2017	Thus, rapamycin-mediated lifespan extension in Lmna-/- mice is in part due to the improvement of skeletal muscle function and can be phenocopied by reduced S6K1 activity, but not 4E-BP1 activation.	Sirolimus	6-15	lamin A	Mus musculus	47-51	
27926859-0	2016	Rapamycin Reverses Metabolic Deficits in Lamin A/C-Deficient Mice.	Sirolimus	0-9	lamin A	Mus musculus	41-50	
27926859-6	2016	Together, our findings indicate that altered mTOR signaling in Lmna-/- mice leads to a lipodystrophic phenotype that can be rescued with rapamycin, highlighting the effect of loss of adipose tissue in Lmna-/- mice and the consequences of altered mTOR signaling.	Sirolimus	137-146	lamin A	Mus musculus	63-67	
22837538-7	2012	In addition,                     inhibition of mTORC1 signaling with rapamycin improves defective                     autophagic-mediated degradation in                         Lmna(-/-) mice.	Sirolimus	69-78	lamin A	Mus musculus	177-181