PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33300153-4	2021	In this study, we showed that rapamycin significantly reduced MYCN mRNA and protein in a concentration-dependent manner in T-ALL cells.	Sirolimus	30-39	MYCN proto-oncogene, bHLH transcription factor	Homo sapiens	62-66	
33300153-8	2021	The results suggest the effects of rapamycin on adult T-ALL is likely mediated by downregulation of MYCN.	Sirolimus	35-44	MYCN proto-oncogene, bHLH transcription factor	Homo sapiens	100-104	
32116708-9	2020	We found the cell death induced by rapamycin and MK-2206 was MYCN-dependent.	Sirolimus	35-44	MYCN proto-oncogene, bHLH transcription factor	Homo sapiens	61-65	
32116708-11	2020	This study delineates the role of MYCN in the cell death induced by combination treatment of rapamycin and MK-2206 in MYCN-amplified NB cells.	Sirolimus	93-102	MYCN proto-oncogene, bHLH transcription factor	Homo sapiens	34-38	
32116708-11	2020	This study delineates the role of MYCN in the cell death induced by combination treatment of rapamycin and MK-2206 in MYCN-amplified NB cells.	Sirolimus	93-102	MYCN proto-oncogene, bHLH transcription factor	Homo sapiens	118-122	
19528451-7	2009	CONCLUSION: The combination of rapamycin or temsirolimus with alphaIR3 decreases MYC-N expression, increases MYC-N phosphorylation and induces apoptosis in vitro which may have clinical relevance to children with neuroblastoma.	Sirolimus	31-40	MYCN proto-oncogene, bHLH transcription factor	Homo sapiens	81-86	
19528451-7	2009	CONCLUSION: The combination of rapamycin or temsirolimus with alphaIR3 decreases MYC-N expression, increases MYC-N phosphorylation and induces apoptosis in vitro which may have clinical relevance to children with neuroblastoma.	Sirolimus	31-40	MYCN proto-oncogene, bHLH transcription factor	Homo sapiens	109-114	
18278068-6	2008	MYCN siRNA significantly blocked VEGF secretion, irrespective of serum conditions, in MYCN-amplified NB cells; this effect was enhanced when combined with rapamycin, an mTOR inhibitor.	Sirolimus	155-164	MYCN proto-oncogene, bHLH transcription factor	Homo sapiens	0-4	
18278068-6	2008	MYCN siRNA significantly blocked VEGF secretion, irrespective of serum conditions, in MYCN-amplified NB cells; this effect was enhanced when combined with rapamycin, an mTOR inhibitor.	Sirolimus	155-164	MYCN proto-oncogene, bHLH transcription factor	Homo sapiens	86-90