PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21228414-7 2011 The weak, nonsignificant overall association between benzene and diffuse large B-cell lymphoma (OR = 1.29, 95% CI: 0.84, 1.98) was increased among women AA for rs2234922 in the microsomal epoxide hydrolase gene, EPHX1 (OR = 1.77, 95% CI: 1.06, 2.97; P(interaction) = 0.06). Benzene 53-60 epoxide hydrolase 1 Homo sapiens 177-205 23797950-0 2013 Microsomal epoxide hydrolase (EPHX1) polymorphisms are associated with aberrant promoter methylation of ERCC3 and hematotoxicity in benzene-exposed workers. Benzene 132-139 epoxide hydrolase 1 Homo sapiens 0-28 23797950-0 2013 Microsomal epoxide hydrolase (EPHX1) polymorphisms are associated with aberrant promoter methylation of ERCC3 and hematotoxicity in benzene-exposed workers. Benzene 132-139 epoxide hydrolase 1 Homo sapiens 30-35 23797950-5 2013 We also observed that an increased number of C allele for rs1051740 in EPHX1 was associated with decreased ERCC3 methylation levels in benzene-exposed workers (P(trend) = 0.001), but not in unexposed controls (P(trend) = 0.379). Benzene 135-142 epoxide hydrolase 1 Homo sapiens 71-76 23797950-6 2013 Interestingly, another EPHX1 SNP (rs2234922) was associated with lower white blood cell (WBC) counts (P(trend) = 0.044) in benzene-exposed workers. Benzene 124-131 epoxide hydrolase 1 Homo sapiens 23-28 23797950-8 2013 Our findings suggest that benzene exposure may be associated with hypermethylation in ERCC3, and that genetic variants in EPHX1 may play an important role in epigenetic changes and hematotoxicity among benzene-exposed workers. Benzene 202-209 epoxide hydrolase 1 Homo sapiens 122-127 22200898-9 2012 The analyses also suggested an interaction between three genes involved in benzene metabolism CYP2E1, NQO1, and EPHX1. Benzene 75-82 epoxide hydrolase 1 Homo sapiens 112-117 21228414-7 2011 The weak, nonsignificant overall association between benzene and diffuse large B-cell lymphoma (OR = 1.29, 95% CI: 0.84, 1.98) was increased among women AA for rs2234922 in the microsomal epoxide hydrolase gene, EPHX1 (OR = 1.77, 95% CI: 1.06, 2.97; P(interaction) = 0.06). Benzene 53-60 epoxide hydrolase 1 Homo sapiens 212-217 18247500-2 2008 SFG electronic spectra were obtained by scanning the frequencies of both incident visible and IR beams and used to study the surface electronic transitions associated with the C-C stretching of benzene rings located at the backbone of MEH-PPV. Benzene 194-201 epoxide hydrolase 1 Homo sapiens 235-238 20951227-11 2011 Finally, a more comprehensive study is warranted in order to better elucidate the involvement of EPHX1 genotypes combination in benzene genotoxicity. Benzene 128-135 epoxide hydrolase 1 Homo sapiens 97-102 19364907-1 2009 Microsomal epoxide hydrolase (EPHX1) biotransforms epoxide derivatives of pharmaceuticals, including metabolites of certain antiepileptic medications, such as phenytoin and carbamazepine, and many environmental epoxides, such as those derived from butadiene, benzene, and carcinogenic polyaromatic hydrocarbons. Benzene 259-266 epoxide hydrolase 1 Homo sapiens 0-28 19364907-1 2009 Microsomal epoxide hydrolase (EPHX1) biotransforms epoxide derivatives of pharmaceuticals, including metabolites of certain antiepileptic medications, such as phenytoin and carbamazepine, and many environmental epoxides, such as those derived from butadiene, benzene, and carcinogenic polyaromatic hydrocarbons. Benzene 259-266 epoxide hydrolase 1 Homo sapiens 30-35 24573875-0 2007 Association of the genetic polymorphism of EPHX1 and EPHX2 with the susceptibility to chronic benzene poisoning. Benzene 94-101 epoxide hydrolase 1 Homo sapiens 43-48 24573875-1 2007 The aim of this study was to explore the association of the genetic polymorphism of EPHX1 and EPHX2 with the susceptibility to chronic benzene poisoning (CBP). Benzene 135-142 epoxide hydrolase 1 Homo sapiens 84-89 15256148-0 2004 [Relationship of genetic polymorphism of microsomal epoxide hydrolase with susceptibility of chronic benzene poisoning]. Benzene 101-108 epoxide hydrolase 1 Homo sapiens 41-69 15584438-3 2004 As regards exposure to benzene, also relevant is the influence of epoxydohydrolase (EPHX) and NAD(P)H quinone oxidoreductase (NQO1) on the urinary excretion of t,t-muconic and phenylmercapturic acids. Benzene 23-30 epoxide hydrolase 1 Homo sapiens 84-88 15256148-1 2004 OBJECTIVE: To explore the relationship between genetic polymorphisms of microsomal epoxide hydrolase (mEH) and susceptibility of chronic benzene poisoning (BP). Benzene 137-144 epoxide hydrolase 1 Homo sapiens 72-100 12655032-2 2003 Polymorphisms in human microsomal epoxide hydrolase (mEH) are associated with an increased risk of developing leukemia, specifically those associated with benzene. Benzene 155-162 epoxide hydrolase 1 Homo sapiens 23-51 11849215-4 2002 We tested the hypothesis that smoking as well as genetic polymorphisms in the microsomal epoxide hydrolase gene (HYL1), an enzyme involved in benzene metabolism, could be risk factors for AML with defined chromosomal abnormalities. Benzene 142-149 epoxide hydrolase 1 Homo sapiens 78-106