PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30714720-7	2019	The potential inhibitory activity of the synthetic tropolones was further evaluated using an enolase inhibition assay, X-ray crystallography, and molecular docking simulations.	Tropolone	51-61	Enolase	Escherichia coli	93-100	
30714720-8	2019	The catalytic activity of enolase was effectively inhibited by both the naturally occurring beta-thujaplicin and the alpha- and beta-substituted phenyl derivatives of tropolones with IC50 values in range of 8-11 muM.	Tropolone	167-177	Enolase	Escherichia coli	26-33	
30714720-10	2019	Our studies validate the antibacterial potential of tropolones with careful consideration of the position and character of chelating moieties for stronger interaction with metal ions and residues in the enolase active site.	Tropolone	52-62	Enolase	Escherichia coli	203-210