PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32245294-2 2019 Our previous work indicated that idarubicin-ZHER2 affibody conjugate has a great potential for the treatment of HER2-overexpressing malignant cell lines but possible induced immune response against constructed conjugate was not addressed. Idarubicin 33-43 erb-b2 receptor tyrosine kinase 2 Homo sapiens 45-49 28460618-0 2019 Specific Targeting of HER2-Positive Head and Neck Squamous Cell Carcinoma Line HN5 by Idarubicin-ZHER2 Affibody Conjugate. Idarubicin 86-96 erb-b2 receptor tyrosine kinase 2 Homo sapiens 22-26 28460618-2 2019 OBJECTIVE: In the current study, HER2-specific affibody molecule, ZHER2:342 (an engineered protein with great affinity for HER2 receptors) was selected for conjugation to idarubicin (an anti-neoplastic antibiotic). Idarubicin 171-181 erb-b2 receptor tyrosine kinase 2 Homo sapiens 33-37 28460618-2 2019 OBJECTIVE: In the current study, HER2-specific affibody molecule, ZHER2:342 (an engineered protein with great affinity for HER2 receptors) was selected for conjugation to idarubicin (an anti-neoplastic antibiotic). Idarubicin 171-181 erb-b2 receptor tyrosine kinase 2 Homo sapiens 67-71 33936221-5 2021 In the current study, we assessed the cytotoxic effects of idarubicin-ZHER2 affibody conjugate on the positive-HER2 cancer cell lines. Idarubicin 59-69 erb-b2 receptor tyrosine kinase 2 Homo sapiens 71-75 33936221-10 2021 Conclusion: The ZHER2-affibody conjugate of idarubicin has a more specific cytotoxic effect compared with idarubicin alone against HER2-overexpressing ovarian cancerous cells. Idarubicin 44-54 erb-b2 receptor tyrosine kinase 2 Homo sapiens 17-21 33936221-10 2021 Conclusion: The ZHER2-affibody conjugate of idarubicin has a more specific cytotoxic effect compared with idarubicin alone against HER2-overexpressing ovarian cancerous cells. Idarubicin 106-116 erb-b2 receptor tyrosine kinase 2 Homo sapiens 17-21 33936221-11 2021 It appears the ZHER2-affibody conjugate of idarubicin has great potential to be implicated as an innovative anti-cancer agent in future clinical trials in patients with HER2-overexpressing ovarian cancer. Idarubicin 43-53 erb-b2 receptor tyrosine kinase 2 Homo sapiens 16-20