PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31748116-4 2020 A proliferation inducing ligand (APRIL) and IL-6 are also known to enhance Gd-IgA1 synthesis in IgAN. Gadolinium 75-77 tumor necrosis factor (ligand) superfamily, member 13 Mus musculus 0-31 31748116-4 2020 A proliferation inducing ligand (APRIL) and IL-6 are also known to enhance Gd-IgA1 synthesis in IgAN. Gadolinium 75-77 tumor necrosis factor (ligand) superfamily, member 13 Mus musculus 33-38 31748116-9 2020 However, siRNA knock-down of APRIL completely suppressed overproduction of Gd-IgA1 induced by IL-6. Gadolinium 75-77 tumor necrosis factor (ligand) superfamily, member 13 Mus musculus 29-34 31748116-11 2020 Furthermore, APRIL and IL-6 pathways each independently mediated TLR9-induced overproduction of Gd-IgA1. Gadolinium 96-98 tumor necrosis factor (ligand) superfamily, member 13 Mus musculus 13-18 31748116-13 2020 Hence, APRIL and IL-6 synergistically, as well as independently, enhance synthesis of Gd-IgA1. Gadolinium 86-88 tumor necrosis factor (ligand) superfamily, member 13 Mus musculus 7-12