PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31831259-4 2020 Further study indicated that GdCl3 could induce the binding of CaSR and TbetaR II and then both of these two receptors translocated from cell membrane to cytoplasm, in this case, TbetaR II on the cell membrane was decreased and then desensitized to the stimulation of its ligand TGF-beta1, so that the activation of its downstream factors such as Smad2 and Smad3 were blocked, finally, ECM expression in mesangial cells were inhibited. Gadolinium 29-34 SMAD family member 3 Rattus norvegicus 357-362