PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 1664725-6 1991 Patch-clamp measurements of ICa indicate that in isolated frog myocytes cGMP inhibits ICa by stimulation of cAMP phosphodiesterase (cGS-PDE), whereas in purified rat ventricular myocytes, cGMP predominantly inhibits ICa via a mechanism involving cGMP-dependent protein kinase (cGMP-PK). isocyanic acid 86-89 phosphodiesterase 2A Rattus norvegicus 132-139 8869231-4 1996 In frog ventricular myocytes, cGMP inhibits ICa by stimulation of a cGMP-stimulated cAMP phosphodiesterase (PDE2), whereas in rat ventricular myocytes, cGMP predominantly inhibits ICa via a mechanism involving activation of a cGMP-dependent protein kinase (cGMP-PK). isocyanic acid 180-183 phosphodiesterase 2A Rattus norvegicus 108-112 8869231-7 1996 Biochemical characterization of the endogenous phosphodiesterases and cGMP-PK in purified cardiac myocytes provide further evidence in support of these mechanisms of cGMP action on ICa. isocyanic acid 181-184 phosphodiesterase 2A Rattus norvegicus 47-65 8869231-4 1996 In frog ventricular myocytes, cGMP inhibits ICa by stimulation of a cGMP-stimulated cAMP phosphodiesterase (PDE2), whereas in rat ventricular myocytes, cGMP predominantly inhibits ICa via a mechanism involving activation of a cGMP-dependent protein kinase (cGMP-PK). isocyanic acid 44-47 phosphodiesterase 2A Rattus norvegicus 108-112 1664725-6 1991 Patch-clamp measurements of ICa indicate that in isolated frog myocytes cGMP inhibits ICa by stimulation of cAMP phosphodiesterase (cGS-PDE), whereas in purified rat ventricular myocytes, cGMP predominantly inhibits ICa via a mechanism involving cGMP-dependent protein kinase (cGMP-PK). isocyanic acid 86-89 phosphodiesterase 2A Rattus norvegicus 132-139 1664725-8 1991 Biochemical characterization of the endogenous PDEs and cGMP-PK in purified cardiac myocytes provided further evidence in support of these mechanisms of cGMP action on ICa. isocyanic acid 168-171 phosphodiesterase 2A Rattus norvegicus 47-51