PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
12969890-1	2004	The goal of this study was to determine whether the protein kinase A (PKA) responsiveness of the cardiac L-type Ca(2+) current (ICa) is affected during transient increases in intracellular Ca(2+) concentration.	isocyanic acid	128-131	protein kinase cAMP-activated catalytic subunit alpha	Rattus norvegicus	52-68	
24412535-0	2014	Stimulation of ICa by basal PKA activity is facilitated by caveolin-3 in cardiac ventricular myocytes.	isocyanic acid	15-18	protein kinase cAMP-activated catalytic subunit alpha	Rattus norvegicus	28-31	
24412535-6	2014	The PKA inhibitor H-89 also reduced basal ICa; however, the inhibitory effects of C3SD and H-89 on basal ICa amplitude were not summative.	isocyanic acid	42-45	protein kinase cAMP-activated catalytic subunit alpha	Rattus norvegicus	4-7	
12969890-1	2004	The goal of this study was to determine whether the protein kinase A (PKA) responsiveness of the cardiac L-type Ca(2+) current (ICa) is affected during transient increases in intracellular Ca(2+) concentration.	isocyanic acid	128-131	protein kinase cAMP-activated catalytic subunit alpha	Rattus norvegicus	70-73	
12969890-3	2004	When measured in 1 or 2 mM Ca(2+) external solution, the aligned myocytes displayed a large ICa that was weakly regulated (20% increase) during stimulation of PKA by 2 microM forskolin.	isocyanic acid	92-95	protein kinase cAMP-activated catalytic subunit alpha	Rattus norvegicus	159-162	
12969890-6	2004	The responsiveness of ICa to PKA was restored during intracellular dialysis with a calmodulin (CaM) inhibitory peptide but not during treatment with inhibitors of protein kinase C, Ca(2+)/CaM-dependent protein kinase, or calcineurin.	isocyanic acid	22-25	protein kinase cAMP-activated catalytic subunit alpha	Rattus norvegicus	29-32	
12969890-7	2004	Adenoviral-mediated expression of a CaM molecule with mutations in all four Ca(2+)-binding sites also increased the PKA sensitivity of ICa.	isocyanic acid	135-138	protein kinase cAMP-activated catalytic subunit alpha	Rattus norvegicus	116-119	
12969890-9	2004	Thus Ca(2+) entering the myocyte through the voltage-gated Ca(2+) channel regulates the PKA responsiveness of ICa.	isocyanic acid	110-113	protein kinase cAMP-activated catalytic subunit alpha	Rattus norvegicus	88-91	
9763626-13	1998	Whole cell patch-clamp analysis showed that the effect of 8-bromo-cAMP, an activator of PKA, on ICa was significantly attenuated during 48 h exposure to 10% O2.7.	isocyanic acid	96-99	protein kinase cAMP-activated catalytic subunit alpha	Rattus norvegicus	88-91	
10591061-4	1999	The D2-induced inhibition of ICa did not depend on protein kinase A (PKA), as it persisted both in the presence of a specific PKA inhibitor (PKI) and in PKA-deficient PC12 cells.	isocyanic acid	29-32	protein kinase cAMP-activated catalytic subunit alpha	Rattus norvegicus	126-129	
8019675-7	1994	Muscarine and oxotremorine exhibited monotone dose-response curves, but oxotremorine-M showed non-linear relationships which became monotonic when cells were intracellularly perfused with inhibitors of protein kinase A (PKA) and C (PKC), suggesting that either PKA or receptor-induced PKC could phosphorylate and thus inactive G-proteins or other unknown proteins involved in inhibitory muscarinic actions on ICa.	isocyanic acid	409-412	protein kinase cAMP-activated catalytic subunit alpha	Rattus norvegicus	220-223	
1963491-7	1990	Addition of protein kinase A catalytic subunit increased the ICa, probably through a phosphorylation process, but did not modify the charge movement.	isocyanic acid	61-64	protein kinase cAMP-activated catalytic subunit alpha	Rattus norvegicus	12-28