PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30848526-8	2019	In summary, administration of baicalin reduces the levels of pro-inflammatory cytokines, possibly through regulation of SIRT1-NF-kB pathway.	baicalin	30-38	sirtuin 1	Rattus norvegicus	120-125	
35447549-11	2022	Furthermore, baicalin elevated sirtuin-1 (SIRT1) level in VPA rats" brain tissues and restored the antioxidant defense mechanisms.	baicalin	13-21	sirtuin 1	Rattus norvegicus	31-40	
35447549-11	2022	Furthermore, baicalin elevated sirtuin-1 (SIRT1) level in VPA rats" brain tissues and restored the antioxidant defense mechanisms.	baicalin	13-21	sirtuin 1	Rattus norvegicus	42-47	
33228635-9	2020	After molecular docking analyses in KEGG and Discovery studio, four protein targets including HNF4A, HMGCR, JAK3, and SIRT1, were screened out, and proved as effective binding with baicalin, wogonoside by SPR.	baicalin	181-189	sirtuin 1	Rattus norvegicus	118-123	
33228635-11	2020	CONCLUSION: Baicalin and wogonoside were screened out to be the active compounds in Gandi capsule and can ameliorate HG-induced podocyte damage by influencing the AMPK and PI3K-AKT signaling pathways by binding with HNF4A, HMGCR, JAK3, and SIRT1.	baicalin	12-20	sirtuin 1	Rattus norvegicus	240-245	
32116682-0	2019	Baicalin Protects Against 17alpha-Ethinylestradiol-Induced Cholestasis via the Sirtuin 1/Hepatic Nuclear Receptor-1alpha/Farnesoid X Receptor Pathway.	baicalin	0-8	sirtuin 1	Rattus norvegicus	79-88	
32116682-8	2019	Finally, we confirmed that baicalin maintains hepatic BA homeostasis and alleviates inflammation through sirtuin 1 (Sirt1)/hepatic nuclear receptor-1alpha (HNF-1alpha)/farnesoid X receptor (FXR) signaling pathway.	baicalin	27-35	sirtuin 1	Rattus norvegicus	105-114	
32116682-8	2019	Finally, we confirmed that baicalin maintains hepatic BA homeostasis and alleviates inflammation through sirtuin 1 (Sirt1)/hepatic nuclear receptor-1alpha (HNF-1alpha)/farnesoid X receptor (FXR) signaling pathway.	baicalin	27-35	sirtuin 1	Rattus norvegicus	116-121	
32116682-9	2019	Thus, baicalin protects against estrogen-induced cholestatic liver injury, and the underlying mechanism involved is related to activation of the Sirt1/HNF-1alpha/FXR signaling pathway.	baicalin	6-14	sirtuin 1	Rattus norvegicus	145-150	
24893986-9	2014	Moreover, the acetylation of NF-kappaB p65 was downregulated by baicalin, which negatively correlates with the baicalin-induced upregulation of sirt1 expression in the same conditions.	baicalin	64-72	sirtuin 1	Rattus norvegicus	144-149	
24893986-9	2014	Moreover, the acetylation of NF-kappaB p65 was downregulated by baicalin, which negatively correlates with the baicalin-induced upregulation of sirt1 expression in the same conditions.	baicalin	111-119	sirtuin 1	Rattus norvegicus	144-149	
24893986-10	2014	The data indicate that CIA in rats can be alleviated by baicalin treatment via relieving joint inflammation, which is related to the suppression of synovial NF-kappaB p65 protein expression and the elevation of its deacetylation by sirt1.	baicalin	56-64	sirtuin 1	Rattus norvegicus	232-237