PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
26760116-5	2016	We hypothesized that IGF-1 and IGF-2 signal via distinct signaling pathways under low-oxygen tension to maintain PMSC multipotency.	Oxygen	86-92	insulin like growth factor 2	Homo sapiens	31-36	
33951651-6	2021	RESULTS: The study demonstrated that cells lacking IGF2 exhibited a significant increase in reactive oxygen levels with apoptosis patterns.	Oxygen	101-107	insulin like growth factor 2	Homo sapiens	51-55	
33026147-0	2020	Novel peptide derived from IGF-2 displays anti-angiogenic activity in vitro and inhibits retinal angiogenesis in a model of oxygen-induced retinopathy.	Oxygen	124-130	insulin like growth factor 2	Homo sapiens	27-32	
26760116-6	2016	In preterm PMSCs, low-oxygen tension increased the expression of IGF-2 and reduced IGF-1.	Oxygen	22-28	insulin like growth factor 2	Homo sapiens	65-70	
26760116-9	2016	This IGF/low oxygen tension-mediated proliferation was receptor dependent because neutralization of the IGF-1R inhibited PMSC proliferation in the presence of IGF-1 and the IR in presence of IGF-2.	Oxygen	13-19	insulin like growth factor 2	Homo sapiens	191-196	
26760116-11	2016	We conclude that low-oxygen tension can modify the IGF-1 or IGF-2 signaling via the IGF-1R and IR in PMSCs.	Oxygen	21-27	insulin like growth factor 2	Homo sapiens	60-65	
14526226-2	2003	Treatment with IGF-I, IGF-II, or IGFBP-LI (2 microg/mL) significantly (P < 0.05) reduced CA1 damage in organotypic hippocampal cultures resulting from 35 minutes of oxygen and glucose deprivation by 71%, 60%, and 40%, respectively.	Oxygen	168-174	insulin like growth factor 2	Homo sapiens	22-28	
22936271-6	2012	PCR confirmed activation of HIF-downstream targets, GLUT1, IGF2, and VEGF under reduced O(2) levels (0.5%).	Oxygen	88-92	insulin like growth factor 2	Homo sapiens	59-63