PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22016779-1 2011 We have previously shown that a massive increase in global SUMOylation occurs during torpor in ground squirrels, and that overexpression of Ubc9 and/or SUMO-1 in cell lines and cortical neurons protects against oxygen and glucose deprivation. Oxygen 211-217 ubiquitin-conjugating enzyme E2I Mus musculus 140-144 23094087-3 2012 We have also shown that overexpression of Ubc9, SUMO-1, or SUMO-2/3 provides protection against ischemic damage in cell lines and cortical neurons exposed to oxygen/glucose deprivation, and in mice exposed to middle cerebral artery occlusion. Oxygen 158-164 ubiquitin-conjugating enzyme E2I Mus musculus 42-46