PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
24700124-7	2014	Neonatal mice from a model of oxygen-induced retinopathy showed suppressed neovascular growth in the retina when endothelial PFKFB3 was genetically deleted or when the mice were treated with a PFKFB3 inhibitor.	Oxygen	30-36	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3	Mus musculus	125-131	
24700124-7	2014	Neonatal mice from a model of oxygen-induced retinopathy showed suppressed neovascular growth in the retina when endothelial PFKFB3 was genetically deleted or when the mice were treated with a PFKFB3 inhibitor.	Oxygen	30-36	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3	Mus musculus	193-199	
34490476-9	2021	Moreover, PFKFB3 silencing notably reversed the HG-induced decrease in oxygen consumption rate, and the HG-induced increase in extracellular acidification rate was rescued by PFKFB3 siRNA.	Oxygen	71-77	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3	Mus musculus	10-16	
33400016-6	2021	Finally, our animal study also showed that intravitreal injection of small interfering RNA of YAP or PFKFB3 dramatically suppressed the neovascular growth in mouse models of choroidal neovascularization and oxygen-induced retinopathy.	Oxygen	207-213	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3	Mus musculus	101-107	
32759274-5	2020	Knockout of 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase (PFKFB3; Pfkfb3 for rodents), a glycolytic activator in myeloid cells, impaired the ability of macrophages/microglia to acquire an angiogenic phenotype, rendering them unable to promote EC proliferation and sprouting and pathological neovascularization in a mouse model of oxygen-induced proliferative retinopathy.	Oxygen	339-345	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3	Mus musculus	67-73	
32759274-5	2020	Knockout of 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase (PFKFB3; Pfkfb3 for rodents), a glycolytic activator in myeloid cells, impaired the ability of macrophages/microglia to acquire an angiogenic phenotype, rendering them unable to promote EC proliferation and sprouting and pathological neovascularization in a mouse model of oxygen-induced proliferative retinopathy.	Oxygen	339-345	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3	Mus musculus	75-81