PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
32364651-5	2020	Cells collected in the middle and at the outlet of the biochips, where oxygen concentrations are lower, were characterized by the upregulation of genes involved in cellular detoxification processes (CYP450), PPAR signaling or arginine biosynthesis.	Oxygen	71-77	peroxisome proliferator activated receptor alpha	Homo sapiens	208-212	
33422127-8	2021	Early prenatal exposure upregulated expression of genes associated with oxygen and nutrient transport, including hypoxia inducible factor 3alpha (HIF3alpha), peroxisome proliferator-activated receptor alpha (PPARalpha), and insulin-like growth binding factor 1 (IGFBP1), in the placenta of CTL diet males exposed to EPS.	Oxygen	72-78	peroxisome proliferator activated receptor alpha	Homo sapiens	158-206	
33422127-8	2021	Early prenatal exposure upregulated expression of genes associated with oxygen and nutrient transport, including hypoxia inducible factor 3alpha (HIF3alpha), peroxisome proliferator-activated receptor alpha (PPARalpha), and insulin-like growth binding factor 1 (IGFBP1), in the placenta of CTL diet males exposed to EPS.	Oxygen	72-78	peroxisome proliferator activated receptor alpha	Homo sapiens	208-217	
29678953-5	2018	In one such population, the Sherpas, lower muscle PPARA expression is associated with a decreased capacity for fatty acid oxidation, potentially improving the efficiency of oxygen utilisation.	Oxygen	173-179	peroxisome proliferator activated receptor alpha	Homo sapiens	50-55	
17926914-5	2007	Moreover, PPARA G (when oxygen pulse was measured) and PGC 1A Gly (when maximal aerobic power and anaerobic threshold (%) of VO2max were measured) alleles were associated with high values of aerobic performance.	Oxygen	24-30	peroxisome proliferator activated receptor alpha	Homo sapiens	10-15	
29762540-1	2018	BACKGROUND: The peroxisome proliferator-activated receptors (PPARA, PPARG, PPARD) and their transcriptional coactivators" (PPARGC1A, PPARGC1B) gene polymorphisms have been associated with muscle morphology, oxygen uptake, power output and endurance performance.	Oxygen	207-213	peroxisome proliferator activated receptor alpha	Homo sapiens	16-59	
29762540-1	2018	BACKGROUND: The peroxisome proliferator-activated receptors (PPARA, PPARG, PPARD) and their transcriptional coactivators" (PPARGC1A, PPARGC1B) gene polymorphisms have been associated with muscle morphology, oxygen uptake, power output and endurance performance.	Oxygen	207-213	peroxisome proliferator activated receptor alpha	Homo sapiens	61-66	
28623968-8	2017	The effect was exacerbated by culture at atmospheric oxygen concentration, where further up-regulation of TFTs including PPARA, CEBPD, HOXA9 and down-regulated TFTs such as JUND/FOS suggest intrinsic heightened key biological and metabolic mechanisms such as glucose use, lipid biosynthesis, protein metabolism; apoptosis, inflammatory responses; and diminished trophoblast proliferation, differentiation, invasion, regeneration, and viability.	Oxygen	53-59	peroxisome proliferator activated receptor alpha	Homo sapiens	121-126	
26159831-4	2015	In response to extended physiological oxygen culture, MEL2 hES cells displayed reduced mtDNA content, mitochondrial mass and expression of metabolic genes TFAM, NRF1, PPARa and MT-ND4.	Oxygen	38-44	peroxisome proliferator activated receptor alpha	Homo sapiens	167-172	
25108226-8	2014	Furthermore, activation and expression of PPARalpha both attenuated the oxidant-induced suppression of mitochondrial O2 consumption in human retinal capillary pericytes.	Oxygen	117-119	peroxisome proliferator activated receptor alpha	Homo sapiens	42-51	
22131314-4	2011	Under conditions associated with acute or chronic oxygen deprivation, PPAR-alpha modulates expression of genes that determine substrate switch (FA vs. glucose) aimed at maintenance of basic cardiac function.	Oxygen	50-56	peroxisome proliferator activated receptor alpha	Homo sapiens	70-80	
21443859-8	2011	Moreover, PPARalpha activation increased the production of CO(2) and acid soluble metabolites, which are products of fatty acid oxidation, and increased oxygen consumption rate in human adipocytes.	Oxygen	153-159	peroxisome proliferator activated receptor alpha	Homo sapiens	10-19	
21113404-3	2010	We sought to investigate how changes in oxygen tension might directly impact muscle PPAR regulation of oxidative genes.	Oxygen	40-46	peroxisome proliferator activated receptor alpha	Homo sapiens	84-88	
21113404-4	2010	Following eight days in culture at 1% oxygen, C(2)C(12) muscle myoblasts displayed a reduction of PGC-1alpha, PPAR-alpha, and RXR-alpha mRNA, as well as CPT-1b and UCP-2 mRNA.	Oxygen	38-44	peroxisome proliferator activated receptor alpha	Homo sapiens	110-120	
11371554-0	2001	Hypoxia inhibits the peroxisome proliferator-activated receptor alpha/retinoid X receptor gene regulatory pathway in cardiac myocytes: a mechanism for O2-dependent modulation of mitochondrial fatty acid oxidation.	Oxygen	151-153	peroxisome proliferator activated receptor alpha	Homo sapiens	21-69