PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30282042-0	2018	Removal of hERG potassium channel affinity through introduction of an oxygen atom: Molecular insights from structure-activity relationships of strychnine and its analogs.	Oxygen	70-76	ETS transcription factor ERG	Homo sapiens	11-15	
32064022-0	2020	Thioridazine Induces Cardiotoxicity via Reactive Oxygen Species-Mediated hERG Channel Deficiency and L-Type Calcium Channel Activation.	Oxygen	49-55	ETS transcription factor ERG	Homo sapiens	73-77	
24144230-6	2013	CONCLUSIONS: We observe that transformations which increased polarity (for example adding an oxygen, or an sp2 nitrogen), decreased lipophilicity (removing carbons), or decreased positive charge consistently reduced hERG inhibition between 3- and 10-fold.	Oxygen	93-99	ETS transcription factor ERG	Homo sapiens	216-220	
1962173-6	1991	The remainder of part 2 is devoted to the many factors influencing the recording of an ERG, notably pupillary diameter, anesthesia, oxygen and glucose supply to the animal, body temperature of the patient, its intraocular pressure and level of retinal adaptation, and finally the age of the patient.	Oxygen	132-138	ETS transcription factor ERG	Homo sapiens	87-90	
5391442-0	1969	[The effect of hyperbaric oxygen on ERG].	Oxygen	26-32	ETS transcription factor ERG	Homo sapiens	36-39	
30282042-8	2018	Compared to their parent compounds, only an oxygen atom was introduced in the nitrogen oxidative isoforms to compensate for the N+ - charge, suggesting that the protonated nitrogen is the key group for strychnine and brucine binding to hERG channel.	Oxygen	44-50	ETS transcription factor ERG	Homo sapiens	236-240	
30282042-12	2018	This study suggests that introduction of an oxygen to compensate for the N+ - charge could be a useful strategy for reducing hERG potency and increasing the safety margin of alkaloid-type compounds in drug development.	Oxygen	44-50	ETS transcription factor ERG	Homo sapiens	125-129