PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
12743373-1	2003	Using DNA microarray and clustering of expressed genes we have analyzed the mechanism of inhibition of wild-type p53-induced apoptosis by the cytokine interleukin 6 (IL-6) and the calcium mobilizer thapsigargin (TG).	Thapsigargin	198-210	tumor protein p53	Homo sapiens	113-116	
25451271-5	2014	We found that treatment with thapsigargin, a stimulator of p53 expression and an inducer of ER stress, decreased Pin1 expression in HCT116 cells.	Thapsigargin	29-41	tumor protein p53	Homo sapiens	59-62	
18604159-6	2008	Several distinct autophagy inducers (e.g., starvation, rapamycin, lithium, tunicamycin and thapsigargin) stimulate the rapid degradation of p53.	Thapsigargin	91-103	tumor protein p53	Homo sapiens	140-143	
17216584-5	2007	The ER stress-inducing agent thapsigargin also induced p53-independent Noxa expression.	Thapsigargin	29-41	tumor protein p53	Homo sapiens	55-58	
16018998-8	2005	Furthermore, the survival rate of p53(-/-)/Mdm2(-/-) cells exposed to thapsigargin was increased when cultured at 32 degrees C compared with 37 degrees C. In conclusion, mild hypothermia protects cells from a variety of stress by p53-dependent and p53-independent mechanisms.	Thapsigargin	70-82	tumor protein p53	Homo sapiens	34-37	
16018998-8	2005	Furthermore, the survival rate of p53(-/-)/Mdm2(-/-) cells exposed to thapsigargin was increased when cultured at 32 degrees C compared with 37 degrees C. In conclusion, mild hypothermia protects cells from a variety of stress by p53-dependent and p53-independent mechanisms.	Thapsigargin	70-82	tumor protein p53	Homo sapiens	230-233	
16018998-8	2005	Furthermore, the survival rate of p53(-/-)/Mdm2(-/-) cells exposed to thapsigargin was increased when cultured at 32 degrees C compared with 37 degrees C. In conclusion, mild hypothermia protects cells from a variety of stress by p53-dependent and p53-independent mechanisms.	Thapsigargin	70-82	tumor protein p53	Homo sapiens	230-233	
12743373-1	2003	Using DNA microarray and clustering of expressed genes we have analyzed the mechanism of inhibition of wild-type p53-induced apoptosis by the cytokine interleukin 6 (IL-6) and the calcium mobilizer thapsigargin (TG).	Thapsigargin	212-214	tumor protein p53	Homo sapiens	113-116	
7750085-4	1995	In contrast, thapsigargin antagonized only drug-induced nuclear accumulation of p53 protein.	Thapsigargin	13-25	tumor protein p53	Homo sapiens	80-83	
12183079-5	2002	Treatment with A23187, a Ca(2+) ionophore, or thapsigargin, a Ca(2+)-ATPase inhibitor, alone enhanced p53 nuclear accumulation, indicating that p53 accumulation is dependent on intracellular Ca(2+) increase.	Thapsigargin	46-58	tumor protein p53	Homo sapiens	102-105	
12183079-5	2002	Treatment with A23187, a Ca(2+) ionophore, or thapsigargin, a Ca(2+)-ATPase inhibitor, alone enhanced p53 nuclear accumulation, indicating that p53 accumulation is dependent on intracellular Ca(2+) increase.	Thapsigargin	46-58	tumor protein p53	Homo sapiens	144-147