PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31316111-6 2019 A classic NRF2 activator, tert-butylhydroquinone (tBHQ), significantly decreased ROS levels and calcium deposition in VSMCs by promoting the nuclear translocation of NRF2 and upregulating P62 and KEAP1 expression. 2-tert-butylhydroquinone 26-48 nucleoporin 62 Homo sapiens 188-191 31316111-6 2019 A classic NRF2 activator, tert-butylhydroquinone (tBHQ), significantly decreased ROS levels and calcium deposition in VSMCs by promoting the nuclear translocation of NRF2 and upregulating P62 and KEAP1 expression. 2-tert-butylhydroquinone 50-54 nucleoporin 62 Homo sapiens 188-191 31316111-8 2019 In conclusion, VSMC calcification can be alleviated by the activation of the KEAP1/NRF2/P62 antioxidative pathway, which could have a protective role when it is exogenously activated by tBHQ. 2-tert-butylhydroquinone 186-190 nucleoporin 62 Homo sapiens 88-91