PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
24097980-7	2013	We also concluded that the increased side chain volume of V280M, in the TM2-TM3 loop, exerts a steric repulsion against Ile-225 at the top of TM1 in the neighboring subunit.	Isoleucine	120-123	tropomyosin 3	Homo sapiens	76-79	
21081645-4	2011	We propose that the structural change of TM5 during the process of GPCR activation involves a local Pro(5.50)-induced unwinding of the helix, acting as a hinge, and the highly conserved hydrophobic Ile(3.40) side chain, acting as a pivot.	Isoleucine	198-201	tropomyosin 3	Homo sapiens	41-44	
21698173-9	2011	CONCLUSIONS/SIGNIFICANCE: Our results suggest that TM5 (Ile-295, Gly-297) is in close proximity to TM8 (Ile-463) in the mammalian transporter, and that the spatial relationship between these domains is altered during the transport cycle.	Isoleucine	56-59	tropomyosin 3	Homo sapiens	51-54	
21698173-9	2011	CONCLUSIONS/SIGNIFICANCE: Our results suggest that TM5 (Ile-295, Gly-297) is in close proximity to TM8 (Ile-463) in the mammalian transporter, and that the spatial relationship between these domains is altered during the transport cycle.	Isoleucine	104-107	tropomyosin 3	Homo sapiens	51-54	
20888323-5	2010	Finally, a bioinformatics study reveals that the triplet amino acid homologies LLT (Leu-Leu-Thr) and AIS (Ala-Ile-Ser) in TM1 and TM3, respectively of the D2R-5-HT(2A)R may be involved in the receptor interface.	Isoleucine	110-113	tropomyosin 3	Homo sapiens	130-133	
16272152-2	2006	Here we described a separate site in hSERT TM3 (Ile-172) that impacts (RS)-CIT recognition when switched to the corresponding Drosophila SERT residue (I172M).	Isoleucine	48-51	tropomyosin 3	Homo sapiens	43-46	
10655481-1	2000	The third transmembrane domain (TM3) of serotonin transporter (SERT) contains two isoleucine residues previously proposed to be involved in binding and transport of serotonin.	Isoleucine	82-92	tropomyosin 3	Homo sapiens	32-35	
10655481-11	2000	They also suggest that Ile-179 in SERT (and Ile-155 in NET) is in a conformationally sensitive part of TM3, which may act as part of an external gate.	Isoleucine	23-26	tropomyosin 3	Homo sapiens	103-106	
10655481-11	2000	They also suggest that Ile-179 in SERT (and Ile-155 in NET) is in a conformationally sensitive part of TM3, which may act as part of an external gate.	Isoleucine	44-47	tropomyosin 3	Homo sapiens	103-106