PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30760093-12 2019 Only dimethyloxalylglycine-loaded clay supernatants taken in the first hours stimulated vascular endothelial growth factor production in fibroblasts. oxalylglycine 5-26 vascular endothelial growth factor A Homo sapiens 88-122 32152325-10 2020 In vitro, DMOG had no proliferative effect on HC, but conditioned supernatant of DMOG-treated HSC induced VEGF-dependent proliferation of LSEC. oxalylglycine 81-85 vascular endothelial growth factor A Homo sapiens 106-110 29360265-7 2018 DMOG-stimulated endothelial cells were treated with two Nox1/Nox4 inhibitors, GKT136901 and GKT137831; cell growth was monitored by DNA quantification, in addition to VEGFA transcript and ROS production. oxalylglycine 0-4 vascular endothelial growth factor A Homo sapiens 167-172 29360265-9 2018 Treatment with DMOG significantly increased endothelial cell expression of Nox4 over 72 h, accompanied by ROS production and increased VEGFA expression. oxalylglycine 15-19 vascular endothelial growth factor A Homo sapiens 135-140 29360265-10 2018 Treatment with GKT136901 or GKT137831 significantly reduced DMOG-induced ROS production and VEGFA expression by endothelial cells, and the inhibitory effect of DMOG on cell growth. oxalylglycine 60-64 vascular endothelial growth factor A Homo sapiens 92-97 29958677-10 2018 Supernatant of DMOG-loaded hydrogels stimulated VEGF production in DPCs in the first hour, whereas the effect of desferrioxamine, L-mimosine, and CoCl2 did not reach a level of significance. oxalylglycine 15-19 vascular endothelial growth factor A Homo sapiens 48-52 29693273-7 2018 Addition of a prolyl hydroxylase inhibitor, dimethyloxalylglycine (DMOG, up to 10 microM), enhanced the levels of HIF-1alpha, and secreted VEGF-A but did not alter the EMT marker levels. oxalylglycine 44-65 vascular endothelial growth factor A Homo sapiens 139-145 29693273-7 2018 Addition of a prolyl hydroxylase inhibitor, dimethyloxalylglycine (DMOG, up to 10 microM), enhanced the levels of HIF-1alpha, and secreted VEGF-A but did not alter the EMT marker levels. oxalylglycine 67-71 vascular endothelial growth factor A Homo sapiens 139-145 21876537-10 2011 DMOG caused upregulation of both HIF and VEGF within 4 h of administration. oxalylglycine 0-4 vascular endothelial growth factor A Homo sapiens 41-45 22866899-6 2012 RESULTS: Expression of 12 angiogenic genes was significantly altered in RA FLS exposed to hypoxia, and seven of these were changed by dimethyloxalylglycine, including ephrin A3 (EFNA3), vascular endothelial growth factor (VEGF), adipokines angiopoietin-like (ANGPTL)-4 and leptin. oxalylglycine 134-155 vascular endothelial growth factor A Homo sapiens 186-220 22866899-6 2012 RESULTS: Expression of 12 angiogenic genes was significantly altered in RA FLS exposed to hypoxia, and seven of these were changed by dimethyloxalylglycine, including ephrin A3 (EFNA3), vascular endothelial growth factor (VEGF), adipokines angiopoietin-like (ANGPTL)-4 and leptin. oxalylglycine 134-155 vascular endothelial growth factor A Homo sapiens 222-226 21876537-11 2011 Addition of VEGF neutralising antibody truncated migratory and proliferative activity of DMOG by about 70%. oxalylglycine 89-93 vascular endothelial growth factor A Homo sapiens 12-16 21876537-14 2011 In conclusion, DMOG stimulates the early phases of gut repair and VEGF-dependent processes appear relevant. oxalylglycine 15-19 vascular endothelial growth factor A Homo sapiens 66-70 21788833-7 2011 RESULTS: In vitro treatment of human umbilical vein endothelial cells during a 24-hour period showed a significant elevation of VEGF expression with dimethyloxalylglycine exposure (92 +- 35 pg/mg total cellular protein) or hypoxia exposure (88 +- 21 pg/mg total cellular protein) compared with controls (23 +- 10 pg/mg total cellular protein) (p < 0.05 for both). oxalylglycine 149-170 vascular endothelial growth factor A Homo sapiens 128-132 34408911-0 2021 Chemically induced hypoxia by dimethyloxalylglycine (DMOG)-loaded nanoporous silica nanoparticles supports endothelial tube formation by sustained VEGF release from adipose tissue-derived stem cells. oxalylglycine 30-51 vascular endothelial growth factor A Homo sapiens 147-151 34408911-0 2021 Chemically induced hypoxia by dimethyloxalylglycine (DMOG)-loaded nanoporous silica nanoparticles supports endothelial tube formation by sustained VEGF release from adipose tissue-derived stem cells. oxalylglycine 53-57 vascular endothelial growth factor A Homo sapiens 147-151 34408911-2 2021 Hypoxia triggering pre-vascularization by enhanced vascular endothelial growth factor (VEGF) expression can be induced chemically by dimethyloxalylglycine (DMOG). oxalylglycine 133-154 vascular endothelial growth factor A Homo sapiens 51-85 34408911-2 2021 Hypoxia triggering pre-vascularization by enhanced vascular endothelial growth factor (VEGF) expression can be induced chemically by dimethyloxalylglycine (DMOG). oxalylglycine 133-154 vascular endothelial growth factor A Homo sapiens 87-91 34408911-2 2021 Hypoxia triggering pre-vascularization by enhanced vascular endothelial growth factor (VEGF) expression can be induced chemically by dimethyloxalylglycine (DMOG). oxalylglycine 156-160 vascular endothelial growth factor A Homo sapiens 51-85 34408911-2 2021 Hypoxia triggering pre-vascularization by enhanced vascular endothelial growth factor (VEGF) expression can be induced chemically by dimethyloxalylglycine (DMOG). oxalylglycine 156-160 vascular endothelial growth factor A Homo sapiens 87-91 34408911-4 2021 Here we evaluated the effects of soluble DMOG and DMOG-loaded NPSNPs on VEGF secretion of adipose tissue-derived stem cells (ASC) and on tube formation by human umbilical vein endothelial cells (HUVEC)-ASC co-cultures. oxalylglycine 50-54 vascular endothelial growth factor A Homo sapiens 72-76 34408911-5 2021 Repeated doses of 100 microM and 500 microM soluble DMOG on ASC resulted in 3- to 7-fold increased VEGF levels on day 9 (P < 0.0001). oxalylglycine 52-56 vascular endothelial growth factor A Homo sapiens 99-103 34408911-6 2021 Same doses of DMOG-NPSNPs enhanced VEGF secretion 7.7-fold (P < 0.0001) which could be maintained until day 12 with 500 microM DMOG-NPSNPs. oxalylglycine 14-18 vascular endothelial growth factor A Homo sapiens 35-39 34408911-6 2021 Same doses of DMOG-NPSNPs enhanced VEGF secretion 7.7-fold (P < 0.0001) which could be maintained until day 12 with 500 microM DMOG-NPSNPs. oxalylglycine 127-131 vascular endothelial growth factor A Homo sapiens 35-39 34408911-8 2021 Thus, DMOG-NPSNPs supported endothelial tube formation by upregulated VEGF secretion from ASC and thus display a promising tool for pre-vascularization of tissue-engineered constructs. oxalylglycine 6-10 vascular endothelial growth factor A Homo sapiens 70-74