PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11194382-6 2000 The short-acting opioids alfentanil and remifentanil provide small volumes of distribution at steady state, a short blood-brain equilibration time and decreased t1/2 beta. Alfentanil 25-35 interleukin 1 receptor like 1 Homo sapiens 161-170 3087231-2 1986 Due to its predictable duration of action, its low volume of distribution in the organism (muscle, fat tissue, skin) and a corresponding low terminal elimination half life (t 1/2 beta), alfentanil seems suitable for use as the last dose of opioid given during NLA. Alfentanil 186-196 interleukin 1 receptor like 1 Homo sapiens 173-183 7586903-15 1995 Speed of onset of effect is very rapid and is similar to that of alfentanil, which is reflected in a t1/2ke0 (a parameter used to characterise the delay between peak blood drug concentration and peak pharmacodynamic effect utilising a theoretical effect compartment) of approximately 1 to 2 minutes. Alfentanil 65-75 interleukin 1 receptor like 1 Homo sapiens 101-108