PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29976873-6 2018 Tianeptine attenuated microglia activation by decreasing the expression of cluster of differentiation 40 (CD40), and major histocompatibility complex class II (MHC II) markers, as well as the release of pro-inflammatory factors: interleukin (IL)-1beta, IL-18, IL-6, tumor necrosis factor alpha (TNF-alpha), and chemokine CC motif ligand 2 (CCL2), and the production of nitric oxide and reactive oxygen species. tianeptine 0-10 tumor necrosis factor Homo sapiens 266-293 29976873-6 2018 Tianeptine attenuated microglia activation by decreasing the expression of cluster of differentiation 40 (CD40), and major histocompatibility complex class II (MHC II) markers, as well as the release of pro-inflammatory factors: interleukin (IL)-1beta, IL-18, IL-6, tumor necrosis factor alpha (TNF-alpha), and chemokine CC motif ligand 2 (CCL2), and the production of nitric oxide and reactive oxygen species. tianeptine 0-10 tumor necrosis factor Homo sapiens 295-304 26640965-6 2016 Our study shows that tianeptine attenuated the LPS-evoked inflammatory activation of microglia by decreasing the expression of proinflammatory cytokines such as IL-1beta, IL-18, IL-6 and tumor necrosis factor alpha (TNF-alpha), the release of nitric oxide (NO) and reactive oxygen species (ROS) as well as the expression of inducible nitric oxide synthase. tianeptine 21-31 tumor necrosis factor Homo sapiens 187-214 26640965-6 2016 Our study shows that tianeptine attenuated the LPS-evoked inflammatory activation of microglia by decreasing the expression of proinflammatory cytokines such as IL-1beta, IL-18, IL-6 and tumor necrosis factor alpha (TNF-alpha), the release of nitric oxide (NO) and reactive oxygen species (ROS) as well as the expression of inducible nitric oxide synthase. tianeptine 21-31 tumor necrosis factor Homo sapiens 216-225 25168152-0 2014 Tianeptine sodium salt suppresses TNF-alpha-induced expression of matrix metalloproteinase-9 in human carcinoma cells via suppression of the PI3K/Akt-mediated NF-kappaB pathway. tianeptine 0-22 tumor necrosis factor Homo sapiens 34-43