PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
32012485-0	2020	Protective effect of Berberine on reproductive function and spermatogenesis in diabetic rats via inhibition of ROS/JAK2/NFkappaB pathway.	Berberine	21-30	Janus kinase 2	Rattus norvegicus	115-119	
32012485-4	2020	Additionally, to investigate the protective effect of monomeric Berberine (BB), that inhibits ROS/JAK2/NFkappaB pathway, in the pathogenesis of DM-induced infertility.	Berberine	64-73	Janus kinase 2	Rattus norvegicus	98-102	
32012485-4	2020	Additionally, to investigate the protective effect of monomeric Berberine (BB), that inhibits ROS/JAK2/NFkappaB pathway, in the pathogenesis of DM-induced infertility.	Berberine	75-77	Janus kinase 2	Rattus norvegicus	98-102	
32012485-15	2020	However, BB could attenuate the ROS production and abrogate activation of JAK2/NFkappaB pathway, thus inhibiting the apoptosis in the testicular cells of DM rats.	Berberine	9-11	Janus kinase 2	Rattus norvegicus	74-78	
32012485-17	2020	BB can play a protective role in preserving the reproductive function and spermatogenesis in DM by inhibiting ROS/JAK2/NFkappaB pathway.	Berberine	0-2	Janus kinase 2	Rattus norvegicus	114-118	
31564534-17	2019	CONCLUSIONS: JAK2 can induce DMED by enhancing oxidative stress and BB can play a role in treating DMED by inhibiting JAK2 and reducing oxidative stress.	Berberine	68-70	Janus kinase 2	Rattus norvegicus	118-122	
31564534-0	2019	Role of JAK2 in the Pathogenesis of Diabetic Erectile Dysfunction and an Intervention With Berberine.	Berberine	91-100	Janus kinase 2	Rattus norvegicus	8-12	
31564534-13	2019	In vivo experiments also confirmed that the erectile function of the DMED+BB group was improved, accompanied by decreased phosphorylated JAK2/JAK2 and decreased oxidative stress.	Berberine	74-76	Janus kinase 2	Rattus norvegicus	137-141	
31564534-13	2019	In vivo experiments also confirmed that the erectile function of the DMED+BB group was improved, accompanied by decreased phosphorylated JAK2/JAK2 and decreased oxidative stress.	Berberine	74-76	Janus kinase 2	Rattus norvegicus	142-146	
31564534-20	2019	Role of JAK2 in the Pathogenesis of Diabetic Erectile Dysfunction and an Intervention With Berberine.	Berberine	91-100	Janus kinase 2	Rattus norvegicus	8-12	
26806299-0	2016	Berberine protects rat heart from ischemia/reperfusion injury via activating JAK2/STAT3 signaling and attenuating endoplasmic reticulum stress.	Berberine	0-9	Janus kinase 2	Rattus norvegicus	77-81	
26806299-11	2016	Pretreatment with BBR also activated the JAK2/STAT3 signaling pathway in heart tissues, and co-treatment with AG490, a specific JAK2/STAT3 inhibitor, blocked not only the protective effects of BBR, but also the inhibition of BBR on MI/R-induced ER stress.	Berberine	18-21	Janus kinase 2	Rattus norvegicus	41-45	
26806299-11	2016	Pretreatment with BBR also activated the JAK2/STAT3 signaling pathway in heart tissues, and co-treatment with AG490, a specific JAK2/STAT3 inhibitor, blocked not only the protective effects of BBR, but also the inhibition of BBR on MI/R-induced ER stress.	Berberine	18-21	Janus kinase 2	Rattus norvegicus	128-132	
26806299-12	2016	In H9C2 cells, treatment with BBR (50 mumol/L) markedly reduced SIR-induced cell apoptosis, oxidative stress and ER stress, which were abolished by transfection with JAK2 siRNA.	Berberine	30-33	Janus kinase 2	Rattus norvegicus	166-170