PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35559886-6 2022 Metal ion, PAHs and surface ROS could also activate the NLRP3 inflammasome through mitochondrial ROS production. Metals 0-5 NLR family pyrin domain containing 3 Homo sapiens 56-61 32194260-0 2020 Tumor Necrosis Factor Primes and Metal Particles Activate the NLRP3 Inflammasome in Human Primary Macrophages. Metals 33-38 NLR family pyrin domain containing 3 Homo sapiens 62-67 31669392-7 2020 These results suggest that internalized metal nanoparticles in oral mucosal epithelial cells activate the NLRP3 inflammasome through the induction of lysosomal damage and autophagy dysfunction. Metals 40-45 NLR family pyrin domain containing 3 Homo sapiens 106-111 31669392-0 2020 Metal nanoparticles-induced activation of NLRP3 inflammasome in human oral keratinocytes is a possible mechanism of oral lichenoid lesions. Metals 0-5 NLR family pyrin domain containing 3 Homo sapiens 42-47 30896160-0 2019 Discovery of Quinazolin-4(3 H)-ones as NLRP3 Inflammasome Inhibitors: Computational Design, Metal-Free Synthesis, and in Vitro Biological Evaluation. Metals 92-97 NLR family pyrin domain containing 3 Homo sapiens 39-44 23794526-1 2013 Recent investigations indicate that innate immune "danger-signaling" pathways mediate metal implant debris induced-inflammatory responses, for example, NALP3 inflammasome. Metals 86-91 NLR family pyrin domain containing 3 Homo sapiens 152-157