PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
27089389-7	2016	In addition, treatment with tolfenamic acid downregulated Smad2 and Smad3 expression, while overexpression of Smad2, but not Smad3, blocked tolfenamic acid-induced suppression of beta-catenin expression.	tolfenamic acid	28-43	SMAD family member 2	Homo sapiens	58-63	
27089389-7	2016	In addition, treatment with tolfenamic acid downregulated Smad2 and Smad3 expression, while overexpression of Smad2, but not Smad3, blocked tolfenamic acid-induced suppression of beta-catenin expression.	tolfenamic acid	140-155	SMAD family member 2	Homo sapiens	110-115	
27089389-10	2016	In conclusion, our findings suggest that tolfenamic acid inhibits growth of colon cancer cells through downregulation of Smad2 and, subsequently, facilitating ubiquitin-proteasome-mediated beta-catenin degradation in colon cancer.	tolfenamic acid	41-56	SMAD family member 2	Homo sapiens	121-126