PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10535965-8 1999 Finally, we show that treatment of BAEC with bradykinin causes a significant increase in cellular ceramide content; the response to bradykinin has an EC(50) of 3 nM and is blocked by the bradykinin B(2)-receptor antagonist HOE140. baec 35-39 kininogen 1 Bos taurus 45-55 10899167-5 2000 Within minutes of adding bradykinin to BAEC, the eNOS-Raf-1-ERK-Akt heteromeric complex dissociated, and it subsequently reassociated following more prolonged agonist stimulation. baec 39-43 kininogen 1 Bos taurus 25-35 10899167-6 2000 Bradykinin treatment of BAEC led to the activation of ERK, associated with an increase in phosphorylation of eNOS; phosphorylation of eNOS by ERK in vitro significantly reduced eNOS enzyme activity. baec 24-28 kininogen 1 Bos taurus 0-10 10535965-8 1999 Finally, we show that treatment of BAEC with bradykinin causes a significant increase in cellular ceramide content; the response to bradykinin has an EC(50) of 3 nM and is blocked by the bradykinin B(2)-receptor antagonist HOE140. baec 35-39 kininogen 1 Bos taurus 132-142 10535965-8 1999 Finally, we show that treatment of BAEC with bradykinin causes a significant increase in cellular ceramide content; the response to bradykinin has an EC(50) of 3 nM and is blocked by the bradykinin B(2)-receptor antagonist HOE140. baec 35-39 kininogen 1 Bos taurus 132-142 7509258-9 1994 Pretreatment of BAEC with palmitoyl-L-carnitine (5-10 microM) inhibited bradykinin induced Ca2+ transients. baec 16-20 kininogen 1 Bos taurus 72-82 9242963-6 1997 Results demonstrate that increasing concentrations of HCY, and not cysteine or glutathione, in the presence of bradykinin at 0.5, 1, and 4 h led to significant (P < 0.05 by ANOVA) time- and dose-dependent increases in RSNO produced by BAEC. baec 238-242 kininogen 1 Bos taurus 111-121 9223444-4 1997 Exposure of BAEC to the eNOS-activating agonists, BK, histamine, or ATP produces transient increases in the amounts of detergent-insoluble caveolin-1. baec 12-16 kininogen 1 Bos taurus 50-52 1665733-4 1991 Pretreatment of BAEC with 4 beta-phorbol 12-myristate 13-acetate (PMA; 100 nM) reduced the magnitude of the initial transient elevation of [Ca2+]i, induced by thrombin (1 mu ml-1), low concentrations of bradykinin (1 nM) or ATP (0.3 microM, 3 microM), but not by higher concentrations of the latter two agonists. baec 16-20 kininogen 1 Bos taurus 203-213 8282000-5 1993 Preincubation of BAEC with CTx, but not with PTx, inhibited bradykinin-dependent production of cyclic GMP. baec 17-21 kininogen 1 Bos taurus 60-70 8100285-14 1993 Similarly, the cGMP increase in MC coincubated with BAEC under bradykinin stimulation was not altered by culturing under high glucose or hypertonic conditions. baec 52-56 kininogen 1 Bos taurus 63-73 2561988-13 1989 These data indicate action of phospholipase C (PLC) on PIP2 after BK stimulation of BAEC with the subsequent production of InsP3 causing the resulting intracellular Ca2+ release. baec 84-88 kininogen 1 Bos taurus 66-68 2388254-7 1990 Efflux of 86Rb+ from BAEC monolayers was stimulated by both bradykinin and ionomycin. baec 21-25 kininogen 1 Bos taurus 60-70