PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10196581-1 1998 The phenylethanolamines, ifenprodil and CP-101,606, are NMDA receptor antagonists with promising neuroprotective properties. ifenprodil 25-35 glutamate ionotropic receptor NMDA type subunit 1 L homeolog Xenopus laevis 56-69 10347236-5 1999 Mutation NR1(D130N) reduced sensitivity to ifenprodil by more than 500-fold, but had little effect on sensitivity to spermine and pH. ifenprodil 43-53 glutamate ionotropic receptor NMDA type subunit 1 L homeolog Xenopus laevis 9-12 10347236-6 1999 Mutations at six other residues in this region of the NR1 subunit reduced the potency and, in some cases, the maximum effect of ifenprodil. ifenprodil 128-138 glutamate ionotropic receptor NMDA type subunit 1 L homeolog Xenopus laevis 54-57 9143010-1 1997 Ifenprodil is an atypical N-methyl-D-aspartate (NMDA) receptor antagonist that selectively blocks receptors containing the NR2B subunit. ifenprodil 0-10 glutamate ionotropic receptor NMDA type subunit 1 L homeolog Xenopus laevis 26-62 9400004-5 1997 Like ifenprodil, Ro 25-6981 blocked NMDA receptor subtypes in an activity-dependent manner. ifenprodil 5-15 glutamate ionotropic receptor NMDA type subunit 1 L homeolog Xenopus laevis 36-49 8838458-5 1996 These results show that the stereoisomers of ifenprodil exhibit a weak though significant stereoselectivity at the NR1A/NR2B NMDA receptor subtype. ifenprodil 45-55 glutamate ionotropic receptor NMDA type subunit 1 L homeolog Xenopus laevis 125-138 19017396-6 2008 RESULTS: Ligand binding of ifenprodil, RO25,6981 and haloperidol on soluble recombinant ATD2B determined from circular dichroism spectroscopy yielded low-to-high micromolar equilibrium constants which concurred with functional IC50 measurement determined in heterologously expressed NR1/NR2B receptors in Xenopus oocytes. ifenprodil 27-37 glutamate ionotropic receptor NMDA type subunit 1 L homeolog Xenopus laevis 283-286 8838458-0 1996 Antagonist properties of the stereoisomers of ifenprodil at NR1A/NR2A and NR1A/NR2B subtypes of the NMDA receptor expressed in Xenopus oocytes. ifenprodil 46-56 glutamate ionotropic receptor NMDA type subunit 1 L homeolog Xenopus laevis 100-113 8838458-1 1996 The NMDA receptor antagonist ifenprodil contains two asymmetric centres which give rise to four stereoisomeric forms of this molecule. ifenprodil 29-39 glutamate ionotropic receptor NMDA type subunit 1 L homeolog Xenopus laevis 4-17 7901753-0 1993 Ifenprodil discriminates subtypes of the N-methyl-D-aspartate receptor: selectivity and mechanisms at recombinant heteromeric receptors. ifenprodil 0-10 glutamate ionotropic receptor NMDA type subunit 1 L homeolog Xenopus laevis 41-70