PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22387411-0 2012 From anti-Parkinson"s drug rasagiline to novel multitarget iron chelators with acetylcholinesterase and monoamine oxidase inhibitory and neuroprotective properties for Alzheimer"s disease. Iron 59-63 acetylcholinesterase (Cartwright blood group) Homo sapiens 79-99 24473150-0 2014 Copper, aluminum, iron and calcium inhibit human acetylcholinesterase in vitro. Iron 18-22 acetylcholinesterase (Cartwright blood group) Homo sapiens 49-69 22778810-3 2010 The identified lead, HLA20A, exhibits little affinity for metal (Fe, Cu, and Zn) ions but can be activated following inhibition of AChE to liberate an active chelator, HLA20. Iron 65-67 acetylcholinesterase (Cartwright blood group) Homo sapiens 131-135 35190910-0 2022 Site-activated multi target iron chelators with acetylcholinesterase (AChE) and monoamine oxidase (MAO) inhibitory activities for Alzheimer"s disease therapy. Iron 28-32 acetylcholinesterase (Cartwright blood group) Homo sapiens 48-68 19485411-2 2009 The novel prochelator HLA20A with improved cytotoxicity shows little affinity for metal ions until it is activated by binding and inhibiting acetylcholinesterase (AChE), releasing an active chelator HLA20 that modulates amyloid precursor protein (APP) regulation and beta-amyloid (Abeta) reduction, suppresses oxidative stress, and passivates excess metal ions (Fe, Cu, and Zn) in the brain. Iron 362-364 acetylcholinesterase (Cartwright blood group) Homo sapiens 141-161 19485411-2 2009 The novel prochelator HLA20A with improved cytotoxicity shows little affinity for metal ions until it is activated by binding and inhibiting acetylcholinesterase (AChE), releasing an active chelator HLA20 that modulates amyloid precursor protein (APP) regulation and beta-amyloid (Abeta) reduction, suppresses oxidative stress, and passivates excess metal ions (Fe, Cu, and Zn) in the brain. Iron 362-364 acetylcholinesterase (Cartwright blood group) Homo sapiens 163-167 1635444-0 1992 [Acetylcholinesterase activity in erythrocytes of workers engaged in the production of iron-manganese alloys]. Iron 87-91 acetylcholinesterase (Cartwright blood group) Homo sapiens 1-21 1635444-1 1992 The activity of acetylcholinesterase in the red blood cells of metallurgy workers producing iron-manganese alloys was statistically less significant than the activity of this enzyme in the control group. Iron 92-96 acetylcholinesterase (Cartwright blood group) Homo sapiens 16-36 18047264-3 2007 The multifunctional compounds show activity against human AChE, are able to inhibit the AChE-induced amyloid-beta aggregation, and chelate metals, such as iron and copper. Iron 155-159 acetylcholinesterase (Cartwright blood group) Homo sapiens 58-62