PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12192037-0 2002 Novel translational control through an iron-responsive element by interaction of multifunctional protein YB-1 and IRP2. Iron 39-43 Y-box binding protein 1 Homo sapiens 105-109 12192037-4 2002 Both in vitro binding and coimmunoprecipitation assays showed the direct interaction of YB-1 and IRP2 in the presence of a high concentration of iron. Iron 145-149 Y-box binding protein 1 Homo sapiens 88-92 12192037-5 2002 RNA gel shift assays showed that YB-1 reduced the formation of the IRP2-mRNA complex when the iron-responsive element of the ferritin mRNA 5" untranslated region (UTR) was used as a probe. Iron 94-98 Y-box binding protein 1 Homo sapiens 33-37 12192037-8 2002 An In vivo coimmunoprecipitation assay showed that IRP2 bound to YB-1 in the presence of iron and a proteasome inhibitor. Iron 89-93 Y-box binding protein 1 Homo sapiens 65-69 12192037-9 2002 The direct interaction of YB-1 and IRP2 provides the first evidence of the involvement of YB-1 in the translational regulation of an iron-related protein. Iron 133-137 Y-box binding protein 1 Homo sapiens 26-30 12192037-9 2002 The direct interaction of YB-1 and IRP2 provides the first evidence of the involvement of YB-1 in the translational regulation of an iron-related protein. Iron 133-137 Y-box binding protein 1 Homo sapiens 90-94