PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
18522836-3	2008	We report here that the Cth2-homologous protein Cth1 is transiently expressed during Fe deprivation and participates in the response to Fe deficiency through the degradation of mRNAs primarily involved in mitochondrially localized activities including respiration and amino acid biosynthesis.	Iron	85-87	putative mRNA-binding protein CTH1	Saccharomyces cerevisiae S288C	48-52	
18715869-2	2008	In response to iron deficiency, the budding yeast Saccharomyces cerevisiae induces the expression of the Cth1 and Cth2 mRNA-binding proteins to promote a genome-wide remodeling of cellular metabolism that contributes to the optimal utilization of iron.	Iron	15-19	putative mRNA-binding protein CTH1	Saccharomyces cerevisiae S288C	105-109	
18715869-2	2008	In response to iron deficiency, the budding yeast Saccharomyces cerevisiae induces the expression of the Cth1 and Cth2 mRNA-binding proteins to promote a genome-wide remodeling of cellular metabolism that contributes to the optimal utilization of iron.	Iron	247-251	putative mRNA-binding protein CTH1	Saccharomyces cerevisiae S288C	105-109	
20008079-1	2010	Budding yeast (Saccharomyces cerevisiae) responds to iron deprivation both by Aft1-Aft2-dependent transcriptional activation of genes involved in cellular iron uptake and by Cth1-Cth2-specific degradation of certain mRNAs coding for iron-dependent biosynthetic components.	Iron	53-57	putative mRNA-binding protein CTH1	Saccharomyces cerevisiae S288C	174-178	
35218933-3	2022	Thus, in response to iron deficiency, transcription factors Aft1 and Aft2 activate the expression of genes implicated in iron acquisition and mobilization, whereas two mRNA-binding proteins, Cth1 and Cth2, posttranscriptionally control iron metabolism.	Iron	121-125	putative mRNA-binding protein CTH1	Saccharomyces cerevisiae S288C	191-195	
18070921-2	2008	CCC1 mRNA is destabilized under low-iron conditions by the binding of Cth1 and Cth2 to the 3" untranslated region (S. Puig, E. Askeland, and D. J. Thiele, Cell 120:99-110, 2005).	Iron	36-40	putative mRNA-binding protein CTH1	Saccharomyces cerevisiae S288C	70-74	
35218933-3	2022	Thus, in response to iron deficiency, transcription factors Aft1 and Aft2 activate the expression of genes implicated in iron acquisition and mobilization, whereas two mRNA-binding proteins, Cth1 and Cth2, posttranscriptionally control iron metabolism.	Iron	236-240	putative mRNA-binding protein CTH1	Saccharomyces cerevisiae S288C	191-195	
23962819-1	2013	Regulation of iron metabolism in Saccharomyces cerevisiae is achieved at the transcriptional level by low (Aft1 and Aft2) and high iron-sensing (Yap5) transcription factors, and at the post-transcriptional level by mRNA-binding proteins (Cth1 and Cth2).	Iron	14-18	putative mRNA-binding protein CTH1	Saccharomyces cerevisiae S288C	238-242	
23962819-3	2013	In addition, new insights into the localization and regulation of Cth1/Cth2 have added another layer of complexity to the cell"s adaptation to iron deficiency.	Iron	143-147	putative mRNA-binding protein CTH1	Saccharomyces cerevisiae S288C	66-70	
22152479-4	2011	Our data support a Mec1/Rad53-independent mechanism in which the iron-regulated Cth1/Cth2 mRNA-binding proteins specifically interact with the WTM1 mRNA in response to iron scarcity and promote its degradation.	Iron	65-69	putative mRNA-binding protein CTH1	Saccharomyces cerevisiae S288C	80-84	
23530061-0	2013	Negative feedback regulation of the yeast CTH1 and CTH2 mRNA binding proteins is required for adaptation to iron deficiency and iron supplementation.	Iron	108-112	putative mRNA-binding protein CTH1	Saccharomyces cerevisiae S288C	42-46	
22152479-4	2011	Our data support a Mec1/Rad53-independent mechanism in which the iron-regulated Cth1/Cth2 mRNA-binding proteins specifically interact with the WTM1 mRNA in response to iron scarcity and promote its degradation.	Iron	168-172	putative mRNA-binding protein CTH1	Saccharomyces cerevisiae S288C	80-84