PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25745543-0 2015 Liver Iron Concentration and Liver Impairment in Relation to Serum IGF-1 Levels in Thalassaemia Major Patients: A Retrospective Study. Iron 6-10 insulin like growth factor 1 Homo sapiens 67-72 27313332-5 2016 This IGF-1R targeted theranostic nanoparticle delivery system has an iron core for non-invasive MR imaging, amphiphilic polymer coating to ensure the biocompatibility as well as for drug loading and conjugation of recombinant human IGF-1 as targeting molecules. Iron 69-73 insulin like growth factor 1 Homo sapiens 5-10 26779261-4 2015 Experimental studies suggest that anabolic hormones such as testosterone, IGF-1, and thyroid hormones are able to increase erythroid mass, erythropoietin synthesis, and iron bioavailability, underlining a potential role of multiple hormonal changes in the anemia of aging. Iron 169-173 insulin like growth factor 1 Homo sapiens 74-79 23775841-11 2014 At early and late CFPE, serum IGF-1 was directly correlated with FEV1 %, serum iron, hemoglobin concentration, and transferrin saturation (TSAT) and indirectly correlated with alpha-1-antitrypsin. Iron 79-83 insulin like growth factor 1 Homo sapiens 30-35 24803998-13 2014 The negative correlation between serum ferritin concentrations and ALT suggests that the impairment of hepatic function negatively affect IGF-I synthesis in these patients due to iron toxicity, even in the absence of hepatitis. Iron 179-183 insulin like growth factor 1 Homo sapiens 138-143 23775841-14 2014 Close correlations among IGF-1 and iron-related hematologic parameters suggest that IGF-1 may participate in CF iron homeostasis, another process that is known to be influenced by CFPE. Iron 35-39 insulin like growth factor 1 Homo sapiens 84-89 16793032-6 2006 CONCLUSION: The IHD patients with low serum iron were associated with a pro-inflammatory state, such as increased TNF-alpha, IL-6, and hsCRP; increased anti-inflammatory activities, such as increased IL-10; decreased cardiac protective factor, such as decreased IGF-I. Iron 44-48 insulin like growth factor 1 Homo sapiens 262-267 21401293-9 2011 In conclusion, the present results indicate a direct effect of iron on 1) secretion of growth factor IGF-I but not steroid hormone progesterone, 2) expression of markers of proliferation (cyclin B1), or 3) apoptosis (caspase-3) of porcine ovarian granulosa cells. Iron 63-67 insulin like growth factor 1 Homo sapiens 101-106 16793032-0 2006 Pro-inflammatory states and IGF-I level in ischemic heart disease with low or high serum iron. Iron 89-93 insulin like growth factor 1 Homo sapiens 28-33 12968678-13 2003 Serum IGF-I correlated with trabecular bone volume (r = 0.6, p = 0.03), inversely with both serum ferritin level (r = -0.6, p < 0.01), and inversely with stainable iron surface (r = -0.53, p = 0.02). Iron 167-171 insulin like growth factor 1 Homo sapiens 6-11 15309428-9 2005 Dietary fiber and vitamin A were positively related to IGF-I (p = 0.004 and 0.03), zinc with IGFB-3 (p = 0.0008), and iron with the IGF-I/IGFBP-3 ratio (p = 0.048), but the differences between the bottom and top quartile were less than 10%. Iron 118-122 insulin like growth factor 1 Homo sapiens 132-137 16462706-0 2004 Reduced insulin growth factor I concentrations in iron-overloaded beta thalassaemic patients with normal growth hormone secretion and liver function. Iron 50-54 insulin like growth factor 1 Homo sapiens 8-31 15487708-0 2004 Association of serum insulin-like growth factor-I and erythropoiesis in relation to body iron status. Iron 89-93 insulin like growth factor 1 Homo sapiens 21-49 15487708-1 2004 This study investigated the associations between serum insulin-like growth factor-I (IGF-I) concentrations and erythropoietic activities in relation to body iron status. Iron 157-161 insulin like growth factor 1 Homo sapiens 55-83 15487708-1 2004 This study investigated the associations between serum insulin-like growth factor-I (IGF-I) concentrations and erythropoietic activities in relation to body iron status. Iron 157-161 insulin like growth factor 1 Homo sapiens 85-90 15487708-3 2004 However, blood hemoglobin and serum iron concentrations averaged 13.4 +/- 0.8 g/dl and 93.7 +/- 41.2 microg/dl in the subjects with IGF-I >809 ng/ml, which were above the values in those with IGF-I <523 ng/ml (12.3 +/- 0.9 g/dl and 50.5 +/- 30.8 microg/dl, p < 0.05, respectively). Iron 36-40 insulin like growth factor 1 Homo sapiens 132-137 15487708-6 2004 Serum IGF-I correlated significantly with FEP (r = -0.45, p <0.05) and serum iron concentrations (r = 0.40, p <0.05) in iron deficient subjects. Iron 80-84 insulin like growth factor 1 Homo sapiens 6-11 15487708-6 2004 Serum IGF-I correlated significantly with FEP (r = -0.45, p <0.05) and serum iron concentrations (r = 0.40, p <0.05) in iron deficient subjects. Iron 126-130 insulin like growth factor 1 Homo sapiens 6-11 15487708-7 2004 In summary, IGF-I seems to have an important relationship to iron metabolism and protoporphyrin synthesis in adolescents. Iron 61-65 insulin like growth factor 1 Homo sapiens 12-17 12716026-3 2003 Treatment with fibroblast growth factor-2, neurotrophin-4, or insulin-like growth factor-1 potentiated neuronal cell death induced by iron-citrate (Fe) or buthionine sulfoximine (BSO), but not ethacrynic acid (EA). Iron 148-150 insulin like growth factor 1 Homo sapiens 62-90 34429676-11 2021 Conclusion: Based on serum ferritin, iron overload is discovered to have a negative correlation with free T4 and insulin-like growth factor-1. Iron 37-41 insulin like growth factor 1 Homo sapiens 113-141 10376783-0 1999 Zinc and IGF-I concentrations in pregnant women with anemia before and after supplementation with iron and/or zinc. Iron 98-102 insulin like growth factor 1 Homo sapiens 9-14 9365067-15 1997 CONCLUSION: Reduced GH secretion and low IGF-I in thalassaemic patients are related to a neurosecretory dysfunction due to iron overload rather than to liver damage. Iron 123-127 insulin like growth factor 1 Homo sapiens 41-46 3291986-4 1988 When the same cells were grown in Fe-supplemented, protein-free medium (RPMI-Fe), insulin and IGF-I caused dose-dependent stimulation of HL60 cell growth with half-maximal stimulation at nanogram concentrations. Iron 34-36 insulin like growth factor 1 Homo sapiens 94-99