PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
26891670-6	2016	Multi-target ligands designed to combat the elevated activity of MAO B in Alzheimer"s and Parkinson"s Diseases incorporate MAO inhibition (usually irreversible) as well as iron chelation, antioxidant or neuroprotective properties.	Iron	172-176	monoamine oxidase B	Homo sapiens	65-70	
17017567-3	2006	Iron chelators (desferal, Vk-28 and clioquinol) but not copper chelators have been shown to be neuroprotective in the 6-hydroxydoapmine and MPTP models of Parkinson"s disease (PD), as are monoamine oxidase B inhibitors such as selegiline and rasagiline.	Iron	0-4	monoamine oxidase B	Homo sapiens	188-207	
15082228-8	2004	Although, the MAO-mediated metabolism of DA increases MAO-B activity, the presence of iron inhibits both MAO-A and MAO-B activities.	Iron	86-90	monoamine oxidase B	Homo sapiens	115-120	
2618593-6	1989	Indeed H2O2 derived from MAO B reaction and autooxidation of dopamine to melanin in the SN can drive the iron dependent Fenton reaction.	Iron	105-109	monoamine oxidase B	Homo sapiens	25-30	
28726524-0	2017	Subnanomolar indazole-5-carboxamide inhibitors of monoamine oxidase B (MAO-B) continued: indications of iron binding, experimental evidence for optimised solubility and brain penetration.	Iron	104-108	monoamine oxidase B	Homo sapiens	71-76	
28685208-0	2017	Iron modulates the activity of monoamine oxidase B in SH-SY5Y cells.	Iron	0-4	monoamine oxidase B	Homo sapiens	31-50	
28685208-2	2017	However, the association of iron with MAO-B activity was poorly understood.	Iron	28-32	monoamine oxidase B	Homo sapiens	38-43	
28685208-3	2017	Here we took advantage of highly sensitive and specific fluorescence probes to examine the change in MAO-B activity in human dopaminergic neuroblastoma (SH-SY5Y) cells upon iron exposure.	Iron	173-177	monoamine oxidase B	Homo sapiens	101-106	
28685208-5	2017	In addition, iron-induced increase in MAO-B probe fluorescence could be prevented by pargyline and other newly developed MAO-B inhibitors, suggesting that it was MAO-B activity-dependent.	Iron	13-17	monoamine oxidase B	Homo sapiens	38-43	
28685208-5	2017	In addition, iron-induced increase in MAO-B probe fluorescence could be prevented by pargyline and other newly developed MAO-B inhibitors, suggesting that it was MAO-B activity-dependent.	Iron	13-17	monoamine oxidase B	Homo sapiens	121-126	
28685208-5	2017	In addition, iron-induced increase in MAO-B probe fluorescence could be prevented by pargyline and other newly developed MAO-B inhibitors, suggesting that it was MAO-B activity-dependent.	Iron	13-17	monoamine oxidase B	Homo sapiens	121-126	
28685208-6	2017	These findings may suggest MAO-B is an important sensor in iron-stressed neuronal cells.	Iron	59-63	monoamine oxidase B	Homo sapiens	27-32