PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
25564462-0	2015	Translational downregulation of HSP90 expression by iron chelators in neuroblastoma cells.	Iron	52-56	heat shock protein 90 alpha family class A member 1	Homo sapiens	32-37	
30660959-6	2019	Here, we demonstrate that upon oxidative stress Hsp90 loses its function in a highly specific non-enzymatic iron-catalyzed oxidation event and its breakdown product, a cleaved form of Hsp90 (Hsp90cl), acquires a new function in mediating the accumulation of actin aggregates.	Iron	108-112	heat shock protein 90 alpha family class A member 1	Homo sapiens	48-53	
30660959-6	2019	Here, we demonstrate that upon oxidative stress Hsp90 loses its function in a highly specific non-enzymatic iron-catalyzed oxidation event and its breakdown product, a cleaved form of Hsp90 (Hsp90cl), acquires a new function in mediating the accumulation of actin aggregates.	Iron	108-112	heat shock protein 90 alpha family class A member 1	Homo sapiens	184-189	
30660959-6	2019	Here, we demonstrate that upon oxidative stress Hsp90 loses its function in a highly specific non-enzymatic iron-catalyzed oxidation event and its breakdown product, a cleaved form of Hsp90 (Hsp90cl), acquires a new function in mediating the accumulation of actin aggregates.	Iron	108-112	heat shock protein 90 alpha family class A member 1	Homo sapiens	191-198	
25564462-7	2015	We functionally confirmed iron-dependent depletion of HSP90 and its client proteins at pharmacologically achievable concentrations of CPX, and we extended this effect to piroctone, 8-hydroxyquinoline, and deferasirox.	Iron	26-30	heat shock protein 90 alpha family class A member 1	Homo sapiens	54-59	
8619831-0	1996	Oxidative stress response in iron-induced acute nephrotoxicity: enhanced expression of heat shock protein 90.	Iron	29-33	heat shock protein 90 alpha family class A member 1	Homo sapiens	87-108	
21413014-0	2012	Hemin, an iron-binding porphyrin, inhibits HIF-1alpha induction through its binding with heat shock protein 90.	Iron	10-14	heat shock protein 90 alpha family class A member 1	Homo sapiens	89-110	
20043217-4	2010	We observed that endocytosis of transferrin, which is involved in the delivery of iron to the cell, was increased after stress induced by heat shock or after incubation with inhibitors of Hsp90 function.	Iron	82-86	heat shock protein 90 alpha family class A member 1	Homo sapiens	188-193	
14976405-0	2004	Heat shock protein 90 recognized as an iron-binding protein associated with the plasma membrane of HeLa cells.	Iron	39-43	heat shock protein 90 alpha family class A member 1	Homo sapiens	0-21	
14976405-3	2004	Employing an iron-binding assay and mass spectrometric analysis, we have identified human Hsp90 as an iron-binding protein in membrane protein preparations of human HeLa cells.	Iron	13-17	heat shock protein 90 alpha family class A member 1	Homo sapiens	90-95	
14976405-3	2004	Employing an iron-binding assay and mass spectrometric analysis, we have identified human Hsp90 as an iron-binding protein in membrane protein preparations of human HeLa cells.	Iron	102-106	heat shock protein 90 alpha family class A member 1	Homo sapiens	90-95	
14976405-5	2004	The iron-binding assay with purified human Hsp90 confirmed iron binding by Hsp90.	Iron	4-8	heat shock protein 90 alpha family class A member 1	Homo sapiens	43-48	
14976405-5	2004	The iron-binding assay with purified human Hsp90 confirmed iron binding by Hsp90.	Iron	4-8	heat shock protein 90 alpha family class A member 1	Homo sapiens	75-80	
14976405-5	2004	The iron-binding assay with purified human Hsp90 confirmed iron binding by Hsp90.	Iron	59-63	heat shock protein 90 alpha family class A member 1	Homo sapiens	43-48	
14976405-5	2004	The iron-binding assay with purified human Hsp90 confirmed iron binding by Hsp90.	Iron	59-63	heat shock protein 90 alpha family class A member 1	Homo sapiens	75-80	
14976405-6	2004	Thus we suggest that Hsp90 is an iron-binding protein associated with the plasma membrane.	Iron	33-37	heat shock protein 90 alpha family class A member 1	Homo sapiens	21-26