PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
28615450-0	2017	Cellular requirements for iron-sulfur cluster insertion into the antiviral radical SAM protein viperin.	Iron	26-30	radical S-adenosyl methionine domain containing 2	Homo sapiens	95-102	
28615450-2	2017	Viperin"s iron-sulfur (Fe/S) cluster is critical for its antiviral activity against many different viruses.	Iron	10-14	radical S-adenosyl methionine domain containing 2	Homo sapiens	0-7	
28615450-2	2017	Viperin"s iron-sulfur (Fe/S) cluster is critical for its antiviral activity against many different viruses.	Iron	23-25	radical S-adenosyl methionine domain containing 2	Homo sapiens	0-7	
24245804-9	2014	Collectively, our data suggest that viperin requires CIAO1 for [4Fe-4S] cluster assembly, and acts through an enzymatic, Fe-S cluster- and SAM-dependent mechanism to inhibit viral RNA synthesis.	Iron	121-125	radical S-adenosyl methionine domain containing 2	Homo sapiens	36-43	
20176015-1	2010	Viperin, an interferon-inducible antiviral protein, is shown to bind an iron-sulfur cluster, based on iron analysis as well as UV-Vis and electron paramagnetic resonance spectroscopic data.	Iron	72-76	radical S-adenosyl methionine domain containing 2	Homo sapiens	0-7	
21527675-6	2011	This interaction with viperin, but not with a mutant lacking the viperin iron-sulfur cluster-binding motif, reduced cellular ATP generation, which resulted in actin cytoskeleton disruption and enhancement of infection.	Iron	73-77	radical S-adenosyl methionine domain containing 2	Homo sapiens	22-29	
23935494-6	2013	We show that all of these metabolic outcomes can be replicated by direct targeting of viperin to mitochondria in the absence of HCMV infection, and that the motif responsible for Fe-S cluster binding by viperin is essential.	Iron	179-183	radical S-adenosyl methionine domain containing 2	Homo sapiens	203-210	
22363738-0	2012	The presence of the iron-sulfur motif is important for the conformational stability of the antiviral protein, Viperin.	Iron	20-24	radical S-adenosyl methionine domain containing 2	Homo sapiens	110-117	
22363738-4	2012	The results show that Viperin is an alpha-beta protein containing iron-sulfur cluster at the center pocket.	Iron	66-70	radical S-adenosyl methionine domain containing 2	Homo sapiens	22-29	
20176015-1	2010	Viperin, an interferon-inducible antiviral protein, is shown to bind an iron-sulfur cluster, based on iron analysis as well as UV-Vis and electron paramagnetic resonance spectroscopic data.	Iron	102-106	radical S-adenosyl methionine domain containing 2	Homo sapiens	0-7