PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34369274-12	2021	Moreover, TFRC activated PTEN induced kinase 1 (PINK1) signaling and induced mitophagy; iron-uptake-induced upregulation of acyl-CoA synthetase long chain family member 4 (ACSL4) was required for mitophagy activation and glutathione peroxidase 4 (GPX4) degradation.	Iron	88-92	PTEN induced kinase 1	Homo sapiens	25-46	
34369274-12	2021	Moreover, TFRC activated PTEN induced kinase 1 (PINK1) signaling and induced mitophagy; iron-uptake-induced upregulation of acyl-CoA synthetase long chain family member 4 (ACSL4) was required for mitophagy activation and glutathione peroxidase 4 (GPX4) degradation.	Iron	88-92	PTEN induced kinase 1	Homo sapiens	48-53	
33023155-0	2020	Systematic Surveys of Iron Homeostasis Mechanisms Reveal Ferritin Superfamily and Nucleotide Surveillance Regulation to be Modified by PINK1 Absence.	Iron	22-26	PTEN induced kinase 1	Homo sapiens	135-140	
35411952-4	2022	We performed temporal metabolomics on mammalian cells treated with deferiprone, a therapeutic iron chelator that stimulates PINK1/PARKIN-independent mitophagy.	Iron	94-98	PTEN induced kinase 1	Homo sapiens	124-129	
33023155-2	2020	In patients suffering from Parkinson"s disease (PD), PINK1-PRKN mutations via deficient mitophagy trigger iron accumulation and reduce lifespan.	Iron	106-110	PTEN induced kinase 1	Homo sapiens	53-58	
24374372-10	2014	However, deleterious effects caused by PINK1 mutations may be alleviated by iron-chelating agents and antioxidant agents with DA quinone-conjugating capacity.	Iron	76-80	PTEN induced kinase 1	Homo sapiens	39-44	
24398127-4	2014	Two articles in EMBO reports, by the Przedborski and Ganley groups, shed light on a new role for processed, cytoplasmic PINK1, and show that depletion of cellular iron levels stimulates PINK1/Parkin-independent mitophagy.	Iron	163-167	PTEN induced kinase 1	Homo sapiens	120-125	
24398127-4	2014	Two articles in EMBO reports, by the Przedborski and Ganley groups, shed light on a new role for processed, cytoplasmic PINK1, and show that depletion of cellular iron levels stimulates PINK1/Parkin-independent mitophagy.	Iron	163-167	PTEN induced kinase 1	Homo sapiens	186-191	
24176932-0	2013	Loss of iron triggers PINK1/Parkin-independent mitophagy.	Iron	8-12	PTEN induced kinase 1	Homo sapiens	22-27