PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35487958-3 2022 Limiting phosphate and iron in growth media induced expression of the receptor-binding domain (RBD) of the SARS-CoV-2 spike protein from the P. tricornutum HASP1 promoter in the wild-type strain and in a histidine auxotrophic strain that alleviates the requirement for antibiotic selection of expression plasmids. Iron 23-27 surface glycoprotein Severe acute respiratory syndrome coronavirus 2 118-123 33804129-4 2021 We found that the highest binding interactions were found with the spike protein (6VYB), with the highest overall binding being observed with Mn-bound Methisazone at -8.3 kcal/mol, followed by Zn and Ca at -8.0 kcal/mol, and Fe and Mg at -7.9 kcal/mol. Iron 225-227 surface glycoprotein Severe acute respiratory syndrome coronavirus 2 67-72 34609882-4 2021 Here, we propose a methodology for investigating the adhesion of the SARS CoV-2 spike glycoprotein on common inorganic surfaces such as aluminum, copper, iron, silica, and ceria oxides as well as metallic gold. Iron 154-158 surface glycoprotein Severe acute respiratory syndrome coronavirus 2 80-85 35340277-7 2022 Our suggested elucidated pathological sequence is: a) spike protein subunit S1 docking with sialylated membrane glycoproteins/receptors (ACE2, CD147), and S2 subunit fusion with the lipid layer; b) cell membrane morpho-functional changes due to the consequent electro-chemical variations and viroporin action, which induce an altered ion channel function and intracellular cation accumulation; c) additional intracellular iron concentration due to a deregulated hepcidin-ferroportin axis, with higher hepcidin levels. Iron 422-426 surface glycoprotein Severe acute respiratory syndrome coronavirus 2 54-59