PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34283874-0 2021 CBS-derived H2S facilitates host colonization of Vibrio cholerae by promoting the iron-dependent catalase activity of KatB. Iron 82-86 cystathionine beta-synthase Mus musculus 0-3 31551410-1 2019 The reduced iron usage induced by the suppression of erythropoiesis is a major cause of the systemic iron overload in CBS knockout (CBS-/-) mice. Iron 12-16 cystathionine beta-synthase Mus musculus 118-121 31551410-1 2019 The reduced iron usage induced by the suppression of erythropoiesis is a major cause of the systemic iron overload in CBS knockout (CBS-/-) mice. Iron 12-16 cystathionine beta-synthase Mus musculus 132-135 31551410-1 2019 The reduced iron usage induced by the suppression of erythropoiesis is a major cause of the systemic iron overload in CBS knockout (CBS-/-) mice. Iron 101-105 cystathionine beta-synthase Mus musculus 118-121 31551410-1 2019 The reduced iron usage induced by the suppression of erythropoiesis is a major cause of the systemic iron overload in CBS knockout (CBS-/-) mice. Iron 101-105 cystathionine beta-synthase Mus musculus 132-135 28859237-0 2018 Cystathionine beta-synthase is required for body iron homeostasis. Iron 49-53 cystathionine beta-synthase Mus musculus 0-27 28859237-2 2018 In view of the exceptionally high expression of CBS in the liver and the common interleukin-6 pathway used in the regulatory systems of hydrogen sulfide and hepcidin, we speculate that CBS is involved in body iron homeostasis. Iron 209-213 cystathionine beta-synthase Mus musculus 48-51 28859237-2 2018 In view of the exceptionally high expression of CBS in the liver and the common interleukin-6 pathway used in the regulatory systems of hydrogen sulfide and hepcidin, we speculate that CBS is involved in body iron homeostasis. Iron 209-213 cystathionine beta-synthase Mus musculus 185-188 28859237-3 2018 We found that CBS knockout (CBS-/- ) mice exhibited anemia and a significant increase in iron content in the serum, liver, spleen, and heart, along with severe damage to the liver, displaying a hemochromatosis-like phenotype. Iron 89-93 cystathionine beta-synthase Mus musculus 14-17 28859237-3 2018 We found that CBS knockout (CBS-/- ) mice exhibited anemia and a significant increase in iron content in the serum, liver, spleen, and heart, along with severe damage to the liver, displaying a hemochromatosis-like phenotype. Iron 89-93 cystathionine beta-synthase Mus musculus 28-31 28859237-6 2018 Importantly, in the liver, absence of CBS caused both a reduction in the transcriptional factor nuclear factor erythroid 2-related factor-2 and an up-regulation of hepcidin that led to a decrease in the iron export protein ferroportin 1. Iron 203-207 cystathionine beta-synthase Mus musculus 38-41 28859237-8 2018 Finally, administration of CBS-overexpressing adenovirus into CBS mutant mice could partially reverse the iron-related phenotype. Iron 106-110 cystathionine beta-synthase Mus musculus 27-30 28859237-8 2018 Finally, administration of CBS-overexpressing adenovirus into CBS mutant mice could partially reverse the iron-related phenotype. Iron 106-110 cystathionine beta-synthase Mus musculus 62-65