PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34464637-7	2021	The protective effect of MAME against iron-overload-induced apoptosis was confirmed by upregulation of protein levels of Bax, Caspase-3, and PARP.	Iron	38-42	poly (ADP-ribose) polymerase family, member 1	Mus musculus	141-145	
29990833-8	2018	Finally, the protective effect of EA against iron overload-induced apoptosis was confirmed by western blotting when its treatment upregulated the expressions of caspase-3 and poly(ADP-ribose) polymerase (PARP) proteins.	Iron	45-49	poly (ADP-ribose) polymerase family, member 1	Mus musculus	175-202	
34281233-6	2021	Iron chelator-induced apoptosis was due to the activation of the MAPK signaling pathway, with increased phosphorylation levels of JNK, p38 and ERK, and ROS generation; in this process, the expression of C-caspase-3 and C-PARP increased.	Iron	0-4	poly (ADP-ribose) polymerase family, member 1	Mus musculus	221-225	
29990833-8	2018	Finally, the protective effect of EA against iron overload-induced apoptosis was confirmed by western blotting when its treatment upregulated the expressions of caspase-3 and poly(ADP-ribose) polymerase (PARP) proteins.	Iron	45-49	poly (ADP-ribose) polymerase family, member 1	Mus musculus	204-208	
22817335-4	2012	Iron (FeSO4) administration also disrupted Bcl-2/Bad protein balance, reduced mitochondrial membrane potential, released cytochrome c and induced the activation of caspases and cleavage of PARP protein.	Iron	0-4	poly (ADP-ribose) polymerase family, member 1	Mus musculus	189-193