PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
15202509-0	2004	Dicoumarol alters cellular redox state and inhibits nuclear factor kappa B to enhance arsenic trioxide-induced apoptosis.	Dicumarol	0-10	nuclear factor kappa B subunit 1	Homo sapiens	52-74	
20430442-9	2010	The VEGF-mediated decrease in amyloid beta is dependent on a functional Flt-1 receptor and is inhibited by dicoumarol, a multifunctional inhibitor of stress-activated protein kinase (SAPK)/JNK and NFkappaB pathways.	Dicumarol	107-117	nuclear factor kappa B subunit 1	Homo sapiens	197-205	
15202509-6	2004	More notably, this enhanced susceptibility was associated with a ROS-mediated inhibition of NF-kappaB activation in which the combinative treatment with dicoumarol prevented NF-kappaB from binding to target DNA.	Dicumarol	153-163	nuclear factor kappa B subunit 1	Homo sapiens	92-101	
15202509-6	2004	More notably, this enhanced susceptibility was associated with a ROS-mediated inhibition of NF-kappaB activation in which the combinative treatment with dicoumarol prevented NF-kappaB from binding to target DNA.	Dicumarol	153-163	nuclear factor kappa B subunit 1	Homo sapiens	174-183	
10531305-9	1999	Consistent with the proposed role of overlapping upstream signaling cascades in activation of NFkappaB, dicoumarol also blocked NFkappaB activation in primary macrophages stimulated with either lipopolysaccharide or TNFalpha.	Dicumarol	104-114	nuclear factor kappa B subunit 1	Homo sapiens	94-102	
10531305-9	1999	Consistent with the proposed role of overlapping upstream signaling cascades in activation of NFkappaB, dicoumarol also blocked NFkappaB activation in primary macrophages stimulated with either lipopolysaccharide or TNFalpha.	Dicumarol	104-114	nuclear factor kappa B subunit 1	Homo sapiens	128-136	
10531305-10	1999	In addition, dicoumarol strongly potentiated TNFalpha-induced apoptosis in HeLa cells, probably by blocking the anti-apoptotic effect of NFkappaB.	Dicumarol	13-23	nuclear factor kappa B subunit 1	Homo sapiens	137-145	
10531305-11	1999	The ability of dicoumarol to simultaneously inhibit SAPK and NFkappaB activation and to potentiate apoptotic cell death suggests that SAPK is not an obligate participant in apoptosis.	Dicumarol	15-25	nuclear factor kappa B subunit 1	Homo sapiens	61-69	
10531305-12	1999	Dicoumarol, currently in clinical use as an oral anticoagulant, represents a potential therapeutic inhibitor of the SAPK and NFkappaB response.	Dicumarol	0-10	nuclear factor kappa B subunit 1	Homo sapiens	125-133