PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32765515-5 2020 HU alone or in combination with hemin promoted the induction of superoxide dismutase-1 (SOD1) and glutathione disulfide-reductase (GSR) in HUVECs and PBMCs, and glutathione peroxidase (GPX1) in PBMCs. Hydroxyurea 0-2 glutathione peroxidase 1 Homo sapiens 185-189 19951064-0 2010 Hydroxyurea-induced expression of glutathione peroxidase 1 in red blood cells of individuals with sickle cell anemia. Hydroxyurea 0-11 glutathione peroxidase 1 Homo sapiens 34-58 19951064-7 2010 RBCs from SCD patients taking hydroxyurea demonstrated 90% higher GPx1 activity than did those from untreated SCD patients, with no differences seen for the other catalytic antioxidants. Hydroxyurea 30-41 glutathione peroxidase 1 Homo sapiens 66-70 19951064-8 2010 Hydroxyurea induced GPx1 expression in multiple cultured cell lines in a manner dependent on both p53 and NO-cGMP signaling pathways. Hydroxyurea 0-11 glutathione peroxidase 1 Homo sapiens 20-24 19951064-9 2010 GPx1 expression represents a previously unrecognized potential benefit of hydroxyurea treatment in SCD patients. Hydroxyurea 74-85 glutathione peroxidase 1 Homo sapiens 0-4