PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
11741479-5	2001	By constructing diarylurea informer libraries based on the structural requirements of Cdk inhibitors in the ATP binding pocket of the Cdk4 model, we were able to identify a potent Cdk4 inhibitor N-(9-oxo-9H-fluoren-4-yl)-N"-pyridin-2-ylurea 15 (IC(50) = 0.10 microM), together with preliminary SAR.	n-(9-oxo-9h-fluoren-4-yl)-n"-pyridin-2-ylurea 15	195-243	cyclin dependent kinase 2	Homo sapiens	86-89