PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33038610-6 2020 The light-mediated AChE expression was triggered by Ca2+, supported by an induction of Ca2+ ionophore A23187 and a blockage by Ca2+ chelator BAPTA-AM. Calcimycin 102-108 acetylcholinesterase (Cartwright blood group) Homo sapiens 19-23 17320203-0 2007 Calcineurin mediates acetylcholinesterase expression during calcium ionophore A23187-induced HeLa cell apoptosis. Calcimycin 78-84 acetylcholinesterase (Cartwright blood group) Homo sapiens 21-41 17320203-6 2007 Overexpression of human NFATc3 and NFATc4 greatly increased the acetylcholinesterase promoter activity in HeLa cells treated with A23187. Calcimycin 130-136 acetylcholinesterase (Cartwright blood group) Homo sapiens 64-84 17000130-0 2007 Regulation of acetylcholinesterase expression by calcium signaling during calcium ionophore A23187- and thapsigargin-induced apoptosis. Calcimycin 92-98 acetylcholinesterase (Cartwright blood group) Homo sapiens 14-34 17000130-3 2007 During apoptosis, treatment of HeLa and MDA-MB-435s cells with the calcium ionophore A23187 resulted in a significant increase in acetylcholinesterase mRNA and protein levels. Calcimycin 85-91 acetylcholinesterase (Cartwright blood group) Homo sapiens 130-150 17000130-5 2007 A23187 also enhanced the stability of acetylcholinesterase mRNA and increased the activity of acetylcholinesterase promoter, effects that were blocked by BAPTA-AM. Calcimycin 0-6 acetylcholinesterase (Cartwright blood group) Homo sapiens 38-58 17000130-5 2007 A23187 also enhanced the stability of acetylcholinesterase mRNA and increased the activity of acetylcholinesterase promoter, effects that were blocked by BAPTA-AM. Calcimycin 0-6 acetylcholinesterase (Cartwright blood group) Homo sapiens 94-114 17000130-7 2007 We further demonstrated that the transactivation of the human acetylcholinesterase promoter by A23187 and thapsigargin was partially mediated by a CCAAT motif within the -1270 to -1248 fragment of the human acetylcholinesterase promoter. Calcimycin 95-101 acetylcholinesterase (Cartwright blood group) Homo sapiens 62-82 17000130-7 2007 We further demonstrated that the transactivation of the human acetylcholinesterase promoter by A23187 and thapsigargin was partially mediated by a CCAAT motif within the -1270 to -1248 fragment of the human acetylcholinesterase promoter. Calcimycin 95-101 acetylcholinesterase (Cartwright blood group) Homo sapiens 207-227 17000130-9 2007 These results strongly suggest that cytosolic Ca(2+) plays a key role in acetylcholinesterase regulation during apoptosis induced by A23187 and thapsigargin. Calcimycin 133-139 acetylcholinesterase (Cartwright blood group) Homo sapiens 73-93 17728068-0 2007 The CCAAT-binding factor CBF/NF-Y regulates the human acetylcholinesterase promoter activity during calcium ionophore A23187-induced cell apoptosis. Calcimycin 118-124 acetylcholinesterase (Cartwright blood group) Homo sapiens 54-74 17728068-1 2007 We previously reported that the expression of acetylcholinesterase during A23187-induced apoptosis of HeLa cells is regulated by Ca(2+) mobilization through the modulation of mRNA stability and acetylcholinesterase promoter activity. Calcimycin 74-80 acetylcholinesterase (Cartwright blood group) Homo sapiens 46-66 17728068-1 2007 We previously reported that the expression of acetylcholinesterase during A23187-induced apoptosis of HeLa cells is regulated by Ca(2+) mobilization through the modulation of mRNA stability and acetylcholinesterase promoter activity. Calcimycin 74-80 acetylcholinesterase (Cartwright blood group) Homo sapiens 194-214 17728068-2 2007 Transactivation of the human acetylcholinesterase promoter by A23187 was partially mediated by the distal CCAAT motif within the -1270 to -1248 fragment of the human acetylcholinesterase promoter, which was bound by the CCAAT binding factor (CBF/NF-Y). Calcimycin 62-68 acetylcholinesterase (Cartwright blood group) Homo sapiens 29-49 17728068-2 2007 Transactivation of the human acetylcholinesterase promoter by A23187 was partially mediated by the distal CCAAT motif within the -1270 to -1248 fragment of the human acetylcholinesterase promoter, which was bound by the CCAAT binding factor (CBF/NF-Y). Calcimycin 62-68 acetylcholinesterase (Cartwright blood group) Homo sapiens 166-186 17728068-3 2007 In the present study, we investigated the molecular mechanisms by which CBF/NF-Y regulates A23187-induced activation of the human acetylcholinesterase promoter. Calcimycin 91-97 acetylcholinesterase (Cartwright blood group) Homo sapiens 130-150 17728068-6 2007 Our results suggest that acetylcholinesterase promoter activation during A23187-induced HeLa cell apoptosis may result partly from the dissociation of CBF/NF-Y from the distal CCAAT motif in the acetylcholinesterase promoter, reversing this suppression. Calcimycin 73-79 acetylcholinesterase (Cartwright blood group) Homo sapiens 25-45 17728068-6 2007 Our results suggest that acetylcholinesterase promoter activation during A23187-induced HeLa cell apoptosis may result partly from the dissociation of CBF/NF-Y from the distal CCAAT motif in the acetylcholinesterase promoter, reversing this suppression. Calcimycin 73-79 acetylcholinesterase (Cartwright blood group) Homo sapiens 195-215 9279214-7 1997 Physostigmine (0.1 mumol/L), an acetylcholinesterase inhibitor, reduced A23187-evoked histamine release by 58%. Calcimycin 72-78 acetylcholinesterase (Cartwright blood group) Homo sapiens 32-52 1913783-0 1991 Calcium and ionophore A23187 stimulates deposition of extracellular matrix and acetylcholinesterase release in cultured myotubes. Calcimycin 22-28 acetylcholinesterase (Cartwright blood group) Homo sapiens 79-99 1913783-3 1991 Scanning and transmission electron-microscopy revealed that treatment with the calcium ionophore A23187, or high extracellular Ca2+ levels (5 mM to 15 mM) produce significant deposits of extracellular matrix around the myotubes, as well as a marked increase in the acetylcholinesterase reaction-product. Calcimycin 97-103 acetylcholinesterase (Cartwright blood group) Homo sapiens 265-285